Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CR534_RS02125 Genome accession   NZ_CP024127
Coordinates   421788..422420 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 14EC001     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 416788..427420
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CR534_RS02100 (CR534_02095) yhfG 416920..417087 (+) 168 WP_000736862.1 YhfG family protein -
  CR534_RS02105 (CR534_02100) fic 417077..417679 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  CR534_RS02110 (CR534_02105) pabA 417711..418274 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  CR534_RS02115 (CR534_02110) argD 418360..419580 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CR534_RS02120 (CR534_02115) yhfK 419647..421737 (-) 2091 WP_123056694.1 YccS/YhfK family putative transporter -
  CR534_RS02125 (CR534_02120) crp 421788..422420 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CR534_RS02135 (CR534_02130) yhfA 422722..423126 (+) 405 WP_001148908.1 OsmC family protein -
  CR534_RS02140 (CR534_02135) prkB 423181..424050 (-) 870 WP_001274680.1 phosphoribulokinase -
  CR534_RS02145 (CR534_02140) yheU 424104..424322 (-) 219 WP_000907085.1 YheU family protein -
  CR534_RS02150 (CR534_02145) yheT 424316..425338 (-) 1023 WP_000057356.1 hydrolase -
  CR534_RS02155 (CR534_02150) yheS 425338..427251 (-) 1914 WP_101981465.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=210710 CR534_RS02125 WP_000242755.1 421788..422420(-) (crp) [Escherichia coli strain 14EC001]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=210710 CR534_RS02125 WP_000242755.1 421788..422420(-) (crp) [Escherichia coli strain 14EC001]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467