Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   HD_RS02995 Genome accession   NC_002940
Coordinates   580323..581000 (+) Length   225 a.a.
NCBI ID   WP_192940796.1    Uniprot ID   -
Organism   [Haemophilus] ducreyi 35000HP     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 575323..586000
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HD_RS02960 (HD0730) rpmG 576143..576313 (-) 171 WP_010944694.1 50S ribosomal protein L33 -
  HD_RS02965 (HD0731) rpmB 576325..576561 (-) 237 WP_010944695.1 50S ribosomal protein L28 -
  HD_RS02970 (HD0732) radC 576722..577393 (-) 672 WP_010944696.1 RadC family protein -
  HD_RS02975 (HD0733) coaBC 577607..578851 (+) 1245 WP_010944697.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  HD_RS02980 (HD0734) dut 578838..579293 (+) 456 WP_041603414.1 dUTP diphosphatase -
  HD_RS02985 (HD0735) slmA 579397..580005 (+) 609 WP_010944699.1 nucleoid occlusion factor SlmA -
  HD_RS02990 (HD0737) - 580014..580232 (+) 219 WP_010944700.1 YheU family protein -
  HD_RS02995 (HD0738) crp 580323..581000 (+) 678 WP_192940796.1 cAMP-activated global transcriptional regulator CRP Regulator
  HD_RS03000 (HD0740) hflX 581070..582419 (-) 1350 WP_010944702.1 ribosome rescue GTPase HflX -
  HD_RS03005 (HD0741) hfq 582457..582762 (-) 306 WP_010944703.1 RNA chaperone Hfq -
  HD_RS03010 (HD0742) miaA 582837..583778 (-) 942 WP_010944704.1 tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA -
  HD_RS03015 (HD0743) mutL 583842..585638 (-) 1797 WP_010944705.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25243.13 Da        Isoelectric Point: 6.5815

>NTDB_id=21069 HD_RS02995 WP_192940796.1 580323..581000(+) (crp) [[Haemophilus] ducreyi 35000HP]
MQDISISTPRLDGEVSPPPSIHDPAVEWFLTHCHIHRYPSKYTLIHAGEEANSLFYIVSGSVAVFIKDDEGKEMILSHLG
QGEFVGEISLFEENTQPRTAWVKTKDACEIAEISYKKFKQLVHVNPDILMYLAAQMACRLRQTSRQVSNLAFLDVTGRIA
QTLMNLAKMPEAMTHPEGMQIKITRQEIGQMVGCSRETVGRILKMLEDEGLISAHGKTIVVYGTR

Nucleotide


Download         Length: 678 bp        

>NTDB_id=21069 HD_RS02995 WP_192940796.1 580323..581000(+) (crp) [[Haemophilus] ducreyi 35000HP]
ATGCAAGATATTTCTATTTCTACACCTCGACTTGATGGAGAGGTTTCCCCGCCTCCTTCGATTCATGATCCTGCGGTAGA
ATGGTTTTTAACGCACTGCCATATTCATCGCTATCCTTCAAAATATACTTTAATTCACGCAGGTGAAGAAGCAAATTCCC
TGTTTTATATTGTCAGTGGTTCTGTGGCTGTCTTTATTAAAGACGATGAAGGCAAAGAAATGATTTTATCACATCTAGGA
CAAGGAGAGTTTGTCGGCGAAATTAGTTTATTTGAAGAAAACACACAGCCAAGAACCGCTTGGGTAAAAACGAAAGATGC
TTGCGAAATTGCAGAAATTTCTTATAAAAAATTTAAACAATTAGTACATGTAAATCCTGACATTTTAATGTATCTTGCTG
CTCAAATGGCTTGTCGCTTACGTCAAACTTCGCGTCAAGTAAGTAATCTTGCTTTTTTAGATGTTACCGGTCGTATTGCG
CAAACATTGATGAATTTAGCCAAAATGCCTGAAGCAATGACGCATCCTGAAGGAATGCAAATTAAAATTACTCGCCAAGA
AATTGGGCAAATGGTGGGCTGCTCACGTGAAACTGTGGGACGCATTTTAAAAATGTTAGAAGATGAAGGTTTAATCTCAG
CCCATGGGAAGACCATAGTTGTTTATGGTACGCGTTAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(37-123)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(157-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

75.862

90.222

0.684
  crp Haemophilus influenzae Rd KW20

73.892

90.222

0.667
  crp Acinetobacter baumannii D1279779

49.5

88.889

0.44

Multiple sequence alignment