Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CSR56_RS03845 Genome accession   NZ_CP024090
Coordinates   748138..748797 (-) Length   219 a.a.
NCBI ID   WP_081508774.1    Uniprot ID   -
Organism   Escherichia coli strain WG5     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 743138..753797
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CSR56_RS03815 (CSR56_03810) parE 743229..745121 (+) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -
  CSR56_RS03820 (CSR56_03815) ygiN 745169..745483 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  CSR56_RS03825 (CSR56_03820) mdaB 745514..746095 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  CSR56_RS03835 (CSR56_03830) ygiZ 746414..746746 (+) 333 WP_000917684.1 DUF2645 family protein -
  CSR56_RS03840 (CSR56_03835) qseC 746792..748141 (-) 1350 WP_000673402.1 quorum sensing histidine kinase QseC -
  CSR56_RS03845 (CSR56_03840) ciaR 748138..748797 (-) 660 WP_081508774.1 quorum sensing response regulator transcription factor QseB Regulator
  CSR56_RS03850 (CSR56_03845) ygiW 748949..749341 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  CSR56_RS03855 (CSR56_03850) ygiV 749394..749876 (+) 483 WP_000183505.1 GyrI-like domain-containing protein -
  CSR56_RS03860 (CSR56_03855) mqsR 750081..750377 (+) 297 WP_000415584.1 type II toxin-antitoxin system toxin MqsR -
  CSR56_RS03865 (CSR56_03860) mqsA 750379..750774 (+) 396 WP_000650107.1 type II toxin-antitoxin system antitoxin MqsA -
  CSR56_RS03870 (CSR56_03865) ygiS 750907..752514 (+) 1608 WP_001295629.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24668.58 Da        Isoelectric Point: 6.7638

>NTDB_id=210466 CSR56_RS03845 WP_081508774.1 748138..748797(-) (ciaR) [Escherichia coli strain WG5]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPHKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=210466 CSR56_RS03845 WP_081508774.1 748138..748797(-) (ciaR) [Escherichia coli strain WG5]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCACAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGTT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365