Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CRN68_RS21720 Genome accession   NZ_CP023960
Coordinates   3989818..3990450 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain FDAARGOS_448     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3984818..3995450
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CRN68_RS21695 (CRN68_21690) yhfG 3984950..3985117 (+) 168 WP_000736860.1 YhfG family protein -
  CRN68_RS21700 (CRN68_21695) fic 3985107..3985709 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  CRN68_RS21705 (CRN68_21700) pabA 3985741..3986304 (+) 564 WP_001521451.1 aminodeoxychorismate synthase component 2 -
  CRN68_RS21710 (CRN68_21705) argD 3986390..3987610 (+) 1221 WP_000963771.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CRN68_RS21715 (CRN68_21710) yhfK 3987677..3989767 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  CRN68_RS21720 (CRN68_21715) crp 3989818..3990450 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CRN68_RS21730 (CRN68_21725) yhfA 3990752..3991156 (+) 405 WP_001148908.1 OsmC family protein -
  CRN68_RS21735 (CRN68_21730) prkB 3991211..3992080 (-) 870 WP_001274680.1 phosphoribulokinase -
  CRN68_RS21740 (CRN68_21735) yheU 3992134..3992352 (-) 219 WP_000907085.1 YheU family protein -
  CRN68_RS21745 (CRN68_21740) yheT 3992346..3993368 (-) 1023 WP_001521449.1 hydrolase -
  CRN68_RS21750 (CRN68_21745) yheS 3993368..3995281 (-) 1914 WP_020232893.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=209523 CRN68_RS21720 WP_000242755.1 3989818..3990450(-) (crp) [Escherichia coli strain FDAARGOS_448]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=209523 CRN68_RS21720 WP_000242755.1 3989818..3990450(-) (crp) [Escherichia coli strain FDAARGOS_448]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGCCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATAGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467