Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CRT35_RS19350 Genome accession   NZ_CP023844
Coordinates   3841801..3842433 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 4/1-1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3836801..3847433
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CRT35_RS19325 (CRT35_20080) yheS 3836970..3838883 (+) 1914 WP_000634830.1 ABC transporter ATP-binding protein -
  CRT35_RS19330 (CRT35_20085) yheT 3838883..3839905 (+) 1023 WP_000057364.1 hydrolase -
  CRT35_RS19335 (CRT35_20090) yheU 3839899..3840117 (+) 219 WP_000907085.1 YheU family protein -
  CRT35_RS19340 (CRT35_20095) prkB 3840171..3841040 (+) 870 WP_001274684.1 phosphoribulokinase -
  CRT35_RS19345 (CRT35_20100) yhfA 3841095..3841499 (-) 405 WP_001148908.1 OsmC family protein -
  CRT35_RS19350 (CRT35_20110) crp 3841801..3842433 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CRT35_RS19355 (CRT35_20115) yhfK 3842484..3844574 (+) 2091 WP_001296470.1 YccS/YhfK family putative transporter -
  CRT35_RS19360 (CRT35_20120) argD 3844641..3845861 (-) 1221 WP_000963794.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CRT35_RS19365 (CRT35_20125) pabA 3845947..3846510 (-) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  CRT35_RS19370 (CRT35_20130) fic 3846542..3847144 (-) 603 WP_001280613.1 putative adenosine monophosphate-protein transferase Fic -
  CRT35_RS19375 (CRT35_20135) yhfG 3847134..3847301 (-) 168 WP_000736858.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=209080 CRT35_RS19350 WP_000242755.1 3841801..3842433(+) (crp) [Escherichia coli strain 4/1-1]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=209080 CRT35_RS19350 WP_000242755.1 3841801..3842433(+) (crp) [Escherichia coli strain 4/1-1]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467