Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CRI72_RS11525 Genome accession   NZ_CP023815
Coordinates   2326024..2326656 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain IMT16316     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2321024..2331656
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CRI72_RS11500 yhfG 2321157..2321324 (+) 168 WP_022646195.1 YhfG family protein -
  CRI72_RS11505 fic 2321314..2321916 (+) 603 WP_022646194.1 putative adenosine monophosphate-protein transferase Fic -
  CRI72_RS11510 pabA 2321948..2322511 (+) 564 WP_022646193.1 aminodeoxychorismate synthase component 2 -
  CRI72_RS11515 argD 2322597..2323820 (+) 1224 WP_016233602.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CRI72_RS11520 yhfK 2323883..2325973 (-) 2091 WP_022646192.1 YccS/YhfK family putative transporter -
  CRI72_RS11525 crp 2326024..2326656 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CRI72_RS11535 yhfA 2326958..2327362 (+) 405 WP_001148908.1 OsmC family protein -
  CRI72_RS11540 prkB 2327417..2328286 (-) 870 WP_001274680.1 phosphoribulokinase -
  CRI72_RS11545 yheU 2328340..2328558 (-) 219 WP_000907085.1 YheU family protein -
  CRI72_RS11550 yheT 2328552..2329574 (-) 1023 WP_022646191.1 hydrolase -
  CRI72_RS11555 yheS 2329574..2331487 (-) 1914 WP_000634789.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=208738 CRI72_RS11525 WP_000242755.1 2326024..2326656(-) (crp) [Escherichia coli strain IMT16316]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=208738 CRI72_RS11525 WP_000242755.1 2326024..2326656(-) (crp) [Escherichia coli strain IMT16316]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment