Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CO706_RS15435 Genome accession   NZ_CP023535
Coordinates   2644277..2644909 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain FDAARGOS_403     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2639277..2649909
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO706_RS15405 (CO706_15405) yheS 2639446..2641359 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  CO706_RS15410 (CO706_15410) yheT 2641359..2642381 (+) 1023 WP_000057405.1 hydrolase -
  CO706_RS15415 (CO706_15415) yheU 2642375..2642593 (+) 219 WP_000907085.1 YheU family protein -
  CO706_RS15420 (CO706_15420) prkB 2642647..2643516 (+) 870 WP_001274680.1 phosphoribulokinase -
  CO706_RS15425 (CO706_15425) yhfA 2643571..2643975 (-) 405 WP_001148908.1 OsmC family protein -
  CO706_RS15435 (CO706_15435) crp 2644277..2644909 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CO706_RS15440 (CO706_15440) yhfK 2644960..2647050 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  CO706_RS15445 (CO706_15445) argD 2647117..2648337 (-) 1221 WP_000963784.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CO706_RS15450 (CO706_15450) pabA 2648423..2648986 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  CO706_RS15455 (CO706_15455) fic 2649018..2649620 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  CO706_RS15460 (CO706_15460) yhfG 2649610..2649777 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=208008 CO706_RS15435 WP_000242755.1 2644277..2644909(+) (crp) [Escherichia coli strain FDAARGOS_403]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=208008 CO706_RS15435 WP_000242755.1 2644277..2644909(+) (crp) [Escherichia coli strain FDAARGOS_403]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467