Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   BK815_RS00910 Genome accession   NZ_CP018199
Coordinates   181559..182188 (+) Length   209 a.a.
NCBI ID   WP_046837881.1    Uniprot ID   A0A1S2MGW6
Organism   Staphylococcus succinus strain 14BME20     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 176559..187188
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BK815_RS00880 - 176594..177313 (+) 720 WP_073504114.1 type 1 glutamine amidotransferase -
  BK815_RS00885 - 177407..178393 (-) 987 WP_073504115.1 FUSC family protein -
  BK815_RS00890 map 178568..179320 (+) 753 WP_073504116.1 type I methionyl aminopeptidase -
  BK815_RS00895 - 179425..179811 (+) 387 WP_073504117.1 hypothetical protein -
  BK815_RS00900 liaF 179828..180529 (+) 702 WP_073504118.1 cell wall-active antibiotics response protein LiaF -
  BK815_RS00905 vraS 180526..181569 (+) 1044 WP_046837882.1 sensor histidine kinase Regulator
  BK815_RS00910 vraR 181559..182188 (+) 630 WP_046837881.1 response regulator transcription factor Regulator
  BK815_RS00915 - 182384..183529 (-) 1146 WP_073504119.1 YihY/virulence factor BrkB family protein -
  BK815_RS00920 - 183745..184029 (-) 285 WP_046837879.1 hypothetical protein -
  BK815_RS00925 - 184029..184499 (-) 471 WP_073504120.1 low molecular weight protein-tyrosine-phosphatase -
  BK815_RS00930 - 184654..184836 (+) 183 WP_083578856.1 DUF1128 family protein -
  BK815_RS00935 - 184852..186093 (+) 1242 WP_073504122.1 aminopeptidase -
  BK815_RS00940 - 186269..186790 (+) 522 WP_073504123.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23702.20 Da        Isoelectric Point: 4.6181

>NTDB_id=207065 BK815_RS00910 WP_046837881.1 181559..182188(+) (vraR) [Staphylococcus succinus strain 14BME20]
MPIKVLFVDDHEMVRIGISSYLSTQPDIDVVGEGKSGNEAIEKAHQLNPDLILMDLLMDDMDGVEATELIKKDLPHIKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAIRKTYNDESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=207065 BK815_RS00910 WP_046837881.1 181559..182188(+) (vraR) [Staphylococcus succinus strain 14BME20]
ATGCCGATTAAAGTTTTATTTGTTGATGATCATGAAATGGTACGAATAGGTATTTCTAGTTATTTATCAACACAACCAGA
TATTGATGTTGTAGGAGAAGGTAAGTCAGGGAATGAAGCGATAGAAAAAGCACATCAACTTAATCCAGATTTAATCCTCA
TGGACTTACTTATGGATGATATGGATGGTGTAGAAGCTACAGAACTTATAAAAAAAGATTTACCTCATATTAAAGTTGTC
ATGTTAACAAGTTACATTGAGGATAATGAAGTATACCGCGCCTTAGATTCAGGTGTGGACAGTTATATTTTAAAAACTAC
AAGTGCAAGTGATATTGCTGAAGCAATACGTAAGACATATAATGATGAGTCTGTATTTGAAGCAGAAGTATTAGTGAAAA
TGAGAAATAGAATGAAACAACGTGCCGAGTTATATGAAATGCTTACAGAACGTGAAATGGAAATTTTATTACTTATTGCT
AAAGGATACTCGAATCAAGAAATAGCTAGTGCTTCACACATTACAATCAAAACCGTCAAGACCCATGTAAGTAATATATT
AAGTAAATTGGAAGTACAAGATAGAACACAAGCAGTTATTTATGCGTTCCAACATAATTTAATACAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1S2MGW6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

88.517

100

0.885
  degU Bacillus subtilis subsp. subtilis str. 168

33.929

100

0.364

Multiple sequence alignment