Detailed information NTG0207064

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: BK815_RS00905
• Genome accession: NZ_CP018199
• Coordinates: 180526..181569 (+)
• Length: 347 a.a.
• NCBI ID: WP_046837882.1
• Uniprot ID: A0A1S2MGQ4
• Organism: Staphylococcus succinus strain 14BME20
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 175526..186569

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BK815_RS00880	-	176594..177313 (+)	720	WP_073504114.1	type 1 glutamine amidotransferase	-
BK815_RS00885	-	177407..178393 (-)	987	WP_073504115.1	FUSC family protein	-
BK815_RS00890	map	178568..179320 (+)	753	WP_073504116.1	type I methionyl aminopeptidase	-
BK815_RS00895	-	179425..179811 (+)	387	WP_073504117.1	hypothetical protein	-
BK815_RS00900	liaF	179828..180529 (+)	702	WP_073504118.1	cell wall-active antibiotics response protein LiaF	-
BK815_RS00905	vraS	180526..181569 (+)	1044	WP_046837882.1	sensor histidine kinase	Regulator
BK815_RS00910	vraR	181559..182188 (+)	630	WP_046837881.1	response regulator transcription factor	Regulator
BK815_RS00915	-	182384..183529 (-)	1146	WP_073504119.1	YihY/virulence factor BrkB family protein	-
BK815_RS00920	-	183745..184029 (-)	285	WP_046837879.1	hypothetical protein	-
BK815_RS00925	-	184029..184499 (-)	471	WP_073504120.1	low molecular weight protein-tyrosine-phosphatase	-
BK815_RS00930	-	184654..184836 (+)	183	WP_083578856.1	DUF1128 family protein	-
BK815_RS00935	-	184852..186093 (+)	1242	WP_073504122.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40023.42 Da
• Isoelectric Point: 6.2448

>NTDB_id=207064 BK815_RS00905 WP_046837882.1 180526..181569(+) (vraS) [Staphylococcus succinus strain 14BME20]
MNHYLRAIGSMLILVYSTFFAIFFIDKVFVNIMYFQGMFYTQIFGIPVLLFLNLLVILLCIIVGSVLAYKINQQNHWLQE
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESQLEAPLDQQIPVLEKMIQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVVDLQKKVPMKVVHDI
EEFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNRTDYLLLRIQDNGKGFNVDEKAEQSYGLKNMRERALEIGAT
YHIVSLPDSGTRIEVKAPLNKEDSYAD

Nucleotide

• Length: 1044 bp

>NTDB_id=207064 BK815_RS00905 WP_046837882.1 180526..181569(+) (vraS) [Staphylococcus succinus strain 14BME20]
ATGAATCACTACTTAAGAGCAATAGGATCCATGTTAATTTTAGTCTATAGTACATTTTTCGCGATATTCTTTATTGATAA
AGTCTTTGTAAACATCATGTACTTTCAAGGTATGTTTTATACACAAATATTTGGAATACCAGTTTTACTATTTTTAAATT
TATTGGTTATATTGCTCTGTATTATAGTAGGATCAGTATTAGCTTATAAAATTAATCAACAGAACCATTGGTTACAAGAA
CAAATTGAACGTTCTATAGAAGGTCAAACTGTAGGGATTAATGATCAAAATATAGAGTTGTATAATGAAACGATAGAATT
ATATCAAACGCTTGTACCATTAAACCAAGAAGTGCACAAATTAAGAATGAAAACACAAAATTTGACGAATGAATCTTATA
ATATCAACGATGTAAAGGTTAAAAAGATTATAGAAGATGAACGACAAAGACTAGCGCGTGAATTACATGATTCTGTAAGC
CAACAATTATTTGCTGCAAGTATGATGCTTTCTGCTATCAAAGAATCCCAATTAGAAGCACCTTTGGATCAACAAATTCC
AGTACTTGAAAAGATGATACAAGACTCTCAATTAGAGATGAGAGCACTATTATTACACTTAAGACCACTCGGCTTAAAAG
ATAAATCGTTAGGTGAAGGGATTAAAGATTTAGTTGTAGATCTACAGAAAAAAGTGCCGATGAAAGTTGTCCATGATATC
GAAGAGTTTAAAGTACCAAAGGGTATTGAAGATCATTTGTTTAGAATTACACAAGAAGCAATTTCTAATACTTTGAGACA
TTCTAAGGGCACTAAGGTTACGATTGAATTGTTTAATAGAACAGATTATTTGCTATTGCGTATACAAGATAATGGTAAAG
GGTTTAATGTAGATGAAAAGGCTGAACAAAGTTATGGGTTGAAAAATATGAGAGAACGCGCATTGGAAATTGGCGCTACA
TATCATATTGTATCTTTACCAGACTCGGGAACGAGGATAGAAGTTAAGGCACCATTAAATAAGGAGGATTCATATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A1S2MGQ4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	88.184	100	0.882