Detailed information NTG0206995

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: CNH35_RS09300
• Genome accession: NZ_CP023390
• Coordinates: 1813146..1814135 (-)
• Length: 329 a.a.
• NCBI ID: WP_000219066.1
• Uniprot ID: P67655
• Organism: Staphylococcus aureus subsp. aureus str. Newman strain NYU_Newman
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1808146..1819135

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CNH35_RS09285 (CNH35_09245)	acsA	1809347..1811053 (-)	1707	WP_000862083.1	acetate--CoA ligase	-
CNH35_RS09290 (CNH35_09250)	-	1811222..1811854 (+)	633	WP_001015996.1	hypothetical protein	-
CNH35_RS09295 (CNH35_09255)	-	1811879..1813048 (+)	1170	WP_001184005.1	acetoin utilization protein AcuC	-
CNH35_RS09300 (CNH35_09260)	ccpA	1813146..1814135 (-)	990	WP_000219066.1	catabolite control protein A	Regulator
CNH35_RS09305 (CNH35_09265)	-	1814208..1814321 (-)	114	WP_001788994.1	hypothetical protein	-
CNH35_RS09310 (CNH35_09270)	-	1814675..1815766 (-)	1092	WP_000066378.1	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase	-
CNH35_RS09315 (CNH35_09275)	-	1816227..1816331 (-)	105	WP_001791758.1	hypothetical protein	-
CNH35_RS09320 (CNH35_09280)	-	1816466..1817983 (-)	1518	WP_000193919.1	hypothetical protein	-
CNH35_RS09325 (CNH35_09285)	-	1818057..1818548 (-)	492	WP_000383814.1	DUF948 domain-containing protein	-

Sequence

Protein

• Length: 329 a.a.
• Molecular weight: 36060.24 Da
• Isoelectric Point: 5.5054

>NTDB_id=206995 CNH35_RS09300 WP_000219066.1 1813146..1814135(-) (ccpA) [Staphylococcus aureus subsp. aureus str. Newman strain NYU_Newman]
MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRLNYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLAR
GLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNID
FTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSGAESYKEGVKAFAKMKGNLPDAI
LCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPH
RIEYRGTTK

Nucleotide

• Length: 990 bp

>NTDB_id=206995 CNH35_RS09300 WP_000219066.1 1813146..1814135(-) (ccpA) [Staphylococcus aureus subsp. aureus str. Newman strain NYU_Newman]
ATGACAGTTACTATATATGATGTAGCAAGAGAAGCGCGTGTCTCTATGGCCACAGTGTCGCGTGTTGTTAATGGGAACCA
AAATGTTAAAGCAGAAACTAAAAATAAAGTTAACGAAGTCATTAAGCGTTTGAATTATCGTCCAAATGCTGTTGCTAGAG
GTTTAGCTAGTAAAAAGACAACAACAGTAGGTGTGATCATTCCAGATATATCTAATATCTATTATTCACAACTTGCTCGT
GGACTTGAAGATATTGCAACAATGTATAAATATCACTCAATTATTTCAAATTCAGATAACGATCCTGAAAAGGAAAAAGA
AATTTTTAATAACTTATTAAGTAAACAGGTTGATGGTATTATTTTCCTTGGTGGTACAATTACTGAAGAAATGAAAGAAT
TGATAAATCAATCATCTGTACCTGTAGTAGTATCAGGAACAAATGGTAAGGATGCACATATAGCATCAGTTAATATTGAT
TTTACTGAAGCTGCGAAAGAAATTACGGGAGAATTAATTGAAAAAGGCGCTAAATCATTTGCTTTAGTAGGTGGAGAACA
TTCTAAAAAAGCTCAAGAAGATGTTTTAGAAGGTTTAACTGAAGTGTTAAATAAAAATGGCCTTCAATTAGGTGATACAT
TGAATTGTTCTGGTGCTGAAAGTTATAAAGAAGGCGTAAAAGCTTTTGCCAAAATGAAAGGCAATTTGCCAGATGCCATT
TTATGTATCAGCGACGAAGAAGCAATTGGTATTATGCATAGTGCAATGGATGCTGGTATTAAAGTTCCAGAGGAATTACA
AATTATTAGTTTCAATAATACACGATTAGTTGAGATGGTTAGACCACAACTTTCTAGTGTTATTCAACCATTATATGATA
TCGGTGCAGTAGGGATGCGCTTATTAACAAAATATATGAACGATGAAAAGATAGAAGAACCAAATGTAGTTTTACCTCAC
AGAATTGAATACCGAGGAACTACAAAATAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (4-49)

• Periplasmic binding protein-like domain (Peripla_BP_3) (171-328)

3D structure

• AlphaFold DB: P67655

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	47.879	100	0.48
ccpA	Streptococcus gordonii str. Challis substr. CH1	47.112	100	0.471
ccpA	Streptococcus pneumoniae D39	46.201	100	0.462