Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   BSR19_RS04950 Genome accession   NZ_CP018187
Coordinates   987501..988841 (+) Length   446 a.a.
NCBI ID   WP_002885062.1    Uniprot ID   A0A0F3HCD0
Organism   Streptococcus salivarius strain ICDC2     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 982501..993841
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR19_RS04920 (BSR19_04990) - 982572..983339 (-) 768 WP_156246672.1 amino acid ABC transporter ATP-binding protein -
  BSR19_RS04925 (BSR19_04995) - 983528..984178 (-) 651 WP_037601175.1 amino acid ABC transporter permease -
  BSR19_RS04930 (BSR19_05000) - 984190..984888 (-) 699 WP_002886251.1 amino acid ABC transporter permease -
  BSR19_RS04935 (BSR19_05005) - 984906..985739 (-) 834 WP_080611395.1 transporter substrate-binding domain-containing protein -
  BSR19_RS04940 (BSR19_05010) - 985749..986516 (-) 768 WP_038675884.1 amino acid ABC transporter ATP-binding protein -
  BSR19_RS04945 (BSR19_05015) vicR 986801..987508 (+) 708 WP_002884978.1 response regulator YycF Regulator
  BSR19_RS04950 (BSR19_05020) vicK 987501..988841 (+) 1341 WP_002885062.1 cell wall metabolism sensor histidine kinase VicK Regulator
  BSR19_RS04955 (BSR19_05025) vicX 988847..989659 (+) 813 WP_013990680.1 MBL fold metallo-hydrolase Regulator
  BSR19_RS04960 (BSR19_05030) - 989719..990078 (+) 360 WP_156246673.1 YbaN family protein -
  BSR19_RS04965 (BSR19_05035) - 990130..991344 (-) 1215 WP_156246674.1 aminoacyltransferase -
  BSR19_RS04970 (BSR19_05040) yidA 991346..992155 (-) 810 WP_002890845.1 sugar-phosphatase -
  BSR19_RS04975 (BSR19_05045) - 992334..993191 (+) 858 WP_156246675.1 GNAT family N-acetyltransferase -
  BSR19_RS04980 (BSR19_05050) - 993283..993669 (+) 387 WP_156246676.1 DUF1934 domain-containing protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50945.21 Da        Isoelectric Point: 5.1606

>NTDB_id=206849 BSR19_RS04950 WP_002885062.1 987501..988841(+) (vicK) [Streptococcus salivarius strain ICDC2]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYRRVKNIRKLTKRVKSLMAGNYNEELRLKGDPELLELADSLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDYETATQMSILDLLDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALDE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLDVEMTNFTAFMTYILNRFDQIKSQETNTGKTYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=206849 BSR19_RS04950 WP_002885062.1 987501..988841(+) (vicK) [Streptococcus salivarius strain ICDC2]
ATGACTAGTATTGGCTTAAACATCACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTGGCTTTCTACTTTAT
TTTTCTGGCTTATCGTGATTATCGACGAGTCAAAAATATTCGAAAGTTGACCAAGAGGGTCAAGTCCTTAATGGCAGGTA
ACTATAACGAGGAGTTACGCTTAAAGGGTGATCCAGAGCTTTTAGAGCTAGCTGACAGCTTGAATGATTTATCGGATGTC
TTTCGTTTGACGCATGAAAATCTAGCCCAGGAAAAAAACCGCTTATCATCAGTCCTTTCTTACATGAGTGATGGGGTTAT
TGCGACAAATCGTCGTGGTCAAATTACCATGATTAATAGCACAGCTCAGCGTTTGTTGAATCTAGATTATGAAACAGCGA
CACAGATGTCCATTTTAGATTTATTAGATGGCGAAAATCCCTATACTTATAGTGAATTGCTCTCTAAGACTCCTGAAATT
CATTTGTCACGTCGAGATGCCAACGATGAGTTTGTGACCTTACGTGTTAATTTTGCCCTTATTCGTAAAGAATCAGGTTT
TATCTCAGGTCTGGTTGCCGTTCTTCACGATGCCACTGAGCAAGAAAAAGAAGAGCGTGAACGTCGACTCTTCGTCTCAA
ACGTTAGTCATGAGTTGCGTACACCTTTGACTTCTGTAAAATCCTATCTGGAGGCACTTGATGATGGTGCTCTCGACGAA
GAGATTGCTCCTAACTTTATCAAAGTTTCTTTGGATGAGACCAATCGTATGATGCGAATGATTTCTGACCTCTTGGCACT
ATCACGTATTGACAATAAGAGTACCCAACTTGACGTTGAGATGACCAATTTCACGGCCTTCATGACCTATATCTTGAATC
GTTTTGATCAGATTAAAAGTCAAGAAACCAATACAGGTAAAACTTACGAAATCATTCGCGATTATCCGGTAAACTCAATT
TGGGTGGAGATTGATACAGATAAGATGACCCAGGTTGTGGATAATATTCTTAATAATGCTATCAAGTATTCGCCTGATGG
TGGTAAGATTACAGTGTCTATGAAGACAACTGATTCACAGTTGATTGTTTCTATTTCTGACCAAGGTTTGGGTATTCCTA
AGAAAGATTTGCCGTTGATTTTCGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCCCAAGGTGGAACTGGTCTA
GGCTTGTCTATTGCAAAAGAAATTATTAAACAACATAAGGGCTTTATTTGGGCTAAGAGTGAGTATGGTAAGGGTTCAAC
TTTTACAATTGTGCTTCCATATGACAAGGATGCCATGATGGTTGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(94-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F3HCD0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92.825

0.684
  micB Streptococcus pneumoniae Cp1015

67.667

97.085

0.657

Multiple sequence alignment