Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CNQ48_RS02220 Genome accession   NZ_CP023386
Coordinates   472613..473245 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 1190     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 467613..478245
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CNQ48_RS02195 (CNQ48_02195) yhfG 467747..467914 (+) 168 WP_000736860.1 YhfG family protein -
  CNQ48_RS02200 (CNQ48_02200) fic 467904..468506 (+) 603 WP_001280628.1 putative adenosine monophosphate-protein transferase Fic -
  CNQ48_RS02205 (CNQ48_02205) pabA 468538..469101 (+) 564 WP_000601857.1 aminodeoxychorismate synthase component 2 -
  CNQ48_RS02210 (CNQ48_02210) argD 469187..470407 (+) 1221 WP_000963781.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CNQ48_RS02215 (CNQ48_02215) yhfK 470472..472562 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  CNQ48_RS02220 (CNQ48_02220) crp 472613..473245 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CNQ48_RS02225 (CNQ48_02225) yhfA 473550..473954 (+) 405 WP_001148908.1 OsmC family protein -
  CNQ48_RS02230 (CNQ48_02230) prkB 474009..474878 (-) 870 WP_001274675.1 phosphoribulokinase -
  CNQ48_RS02235 (CNQ48_02235) yheU 474932..475150 (-) 219 WP_000907085.1 YheU family protein -
  CNQ48_RS02240 (CNQ48_02240) yheT 475144..476166 (-) 1023 WP_000057375.1 hydrolase -
  CNQ48_RS02245 (CNQ48_02245) yheS 476166..478079 (-) 1914 WP_000634840.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=206765 CNQ48_RS02220 WP_000242755.1 472613..473245(-) (crp) [Escherichia coli strain 1190]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=206765 CNQ48_RS02220 WP_000242755.1 472613..473245(-) (crp) [Escherichia coli strain 1190]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGCCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment