Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CNQ52_RS02305 Genome accession   NZ_CP023366
Coordinates   486624..487256 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 1428     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 481624..492256
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CNQ52_RS02280 (CNQ52_02280) yhfG 481757..481924 (+) 168 WP_022646195.1 YhfG family protein -
  CNQ52_RS02285 (CNQ52_02285) fic 481914..482516 (+) 603 WP_022646194.1 putative adenosine monophosphate-protein transferase Fic -
  CNQ52_RS02290 (CNQ52_02290) pabA 482548..483111 (+) 564 WP_022646193.1 aminodeoxychorismate synthase component 2 -
  CNQ52_RS02295 (CNQ52_02295) argD 483197..484420 (+) 1224 WP_016233602.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CNQ52_RS02300 (CNQ52_02300) yhfK 484483..486573 (-) 2091 WP_022646192.1 YccS/YhfK family putative transporter -
  CNQ52_RS02305 (CNQ52_02305) crp 486624..487256 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CNQ52_RS02315 (CNQ52_02315) yhfA 487558..487962 (+) 405 WP_001148908.1 OsmC family protein -
  CNQ52_RS02320 (CNQ52_02320) prkB 488017..488886 (-) 870 WP_001274680.1 phosphoribulokinase -
  CNQ52_RS02325 (CNQ52_02325) yheU 488940..489158 (-) 219 WP_000907085.1 YheU family protein -
  CNQ52_RS02330 (CNQ52_02330) yheT 489152..490174 (-) 1023 WP_022646191.1 hydrolase -
  CNQ52_RS02335 (CNQ52_02335) yheS 490174..492087 (-) 1914 WP_000634789.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=206446 CNQ52_RS02305 WP_000242755.1 486624..487256(-) (crp) [Escherichia coli strain 1428]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=206446 CNQ52_RS02305 WP_000242755.1 486624..487256(-) (crp) [Escherichia coli strain 1428]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment