Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CNQ53_RS03210 Genome accession   NZ_CP023364
Coordinates   488283..488915 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 144     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 483283..493915
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CNQ53_RS03185 (CNQ53_03180) yhfG 483416..483583 (+) 168 WP_000736860.1 YhfG family protein -
  CNQ53_RS03190 (CNQ53_03185) fic 483573..484175 (+) 603 WP_001280645.1 putative adenosine monophosphate-protein transferase Fic -
  CNQ53_RS03195 (CNQ53_03190) pabA 484207..484770 (+) 564 WP_001551743.1 aminodeoxychorismate synthase component 2 -
  CNQ53_RS03200 (CNQ53_03195) argD 484856..486079 (+) 1224 WP_001551741.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CNQ53_RS03205 (CNQ53_03200) yhfK 486142..488232 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  CNQ53_RS03210 (CNQ53_03205) crp 488283..488915 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CNQ53_RS03220 (CNQ53_03215) yhfA 489217..489621 (+) 405 WP_001148908.1 OsmC family protein -
  CNQ53_RS03225 (CNQ53_03220) prkB 489676..490545 (-) 870 WP_001274680.1 phosphoribulokinase -
  CNQ53_RS03230 (CNQ53_03225) yheU 490599..490817 (-) 219 WP_000907085.1 YheU family protein -
  CNQ53_RS03235 (CNQ53_03230) yheT 490811..491833 (-) 1023 WP_001551740.1 hydrolase -
  CNQ53_RS03240 (CNQ53_03235) yheS 491833..493752 (-) 1920 WP_001551739.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=206365 CNQ53_RS03210 WP_000242755.1 488283..488915(-) (crp) [Escherichia coli strain 144]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=206365 CNQ53_RS03210 WP_000242755.1 488283..488915(-) (crp) [Escherichia coli strain 144]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGATGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment