Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CJU64_RS19835 Genome accession   NZ_CP023346
Coordinates   3783694..3784326 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain ETEC-2265     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3778694..3789326
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CJU64_RS19805 (CJU64_19805) yheS 3778863..3780776 (+) 1914 WP_001404121.1 ABC transporter ATP-binding protein -
  CJU64_RS19810 (CJU64_19810) yheT 3780776..3781798 (+) 1023 WP_000057405.1 hydrolase -
  CJU64_RS19815 (CJU64_19815) yheU 3781792..3782010 (+) 219 WP_000907085.1 YheU family protein -
  CJU64_RS19820 (CJU64_19820) prkB 3782064..3782933 (+) 870 WP_001274680.1 phosphoribulokinase -
  CJU64_RS19825 (CJU64_19825) yhfA 3782988..3783392 (-) 405 WP_001148908.1 OsmC family protein -
  CJU64_RS19835 (CJU64_19835) crp 3783694..3784326 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CJU64_RS19840 (CJU64_19840) yhfK 3784377..3786467 (+) 2091 WP_001345983.1 YccS/YhfK family putative transporter -
  CJU64_RS19845 (CJU64_19845) argD 3786534..3787754 (-) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CJU64_RS19850 (CJU64_19850) pabA 3787840..3788403 (-) 564 WP_000601844.1 aminodeoxychorismate synthase component 2 -
  CJU64_RS19855 (CJU64_19855) fic 3788435..3789037 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  CJU64_RS19860 (CJU64_19860) yhfG 3789027..3789194 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=205998 CJU64_RS19835 WP_000242755.1 3783694..3784326(+) (crp) [Escherichia coli strain ETEC-2265]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=205998 CJU64_RS19835 WP_000242755.1 3783694..3784326(+) (crp) [Escherichia coli strain ETEC-2265]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTTCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment