Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CLH63_RS26455 Genome accession   NZ_CP023255
Coordinates   5477256..5477900 (-) Length   214 a.a.
NCBI ID   WP_003085214.1    Uniprot ID   A0A0H2ZLY6
Organism   Pseudomonas aeruginosa strain CCUG 70744     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5472256..5482900
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CLH63_RS26425 (CLH63_26435) - 5473116..5473745 (+) 630 WP_003113192.1 glycoside hydrolase family 19 protein -
  CLH63_RS26430 (CLH63_26440) - 5473742..5474104 (+) 363 WP_014602438.1 hypothetical protein -
  CLH63_RS26435 (CLH63_26445) - 5474101..5474358 (+) 258 WP_023464274.1 hypothetical protein -
  CLH63_RS26440 (CLH63_26450) - 5474706..5475311 (+) 606 WP_003113175.1 aminodeoxychorismate/anthranilate synthase component II -
  CLH63_RS26445 (CLH63_26455) trpD 5475313..5476362 (+) 1050 WP_003085203.1 anthranilate phosphoribosyltransferase -
  CLH63_RS26450 (CLH63_26460) trpC 5476359..5477195 (+) 837 WP_003085205.1 indole-3-glycerol phosphate synthase TrpC -
  CLH63_RS26455 (CLH63_26465) crp 5477256..5477900 (-) 645 WP_003085214.1 cAMP-activated global transcriptional regulator CRP Regulator
  CLH63_RS26460 (CLH63_26470) - 5478172..5478594 (+) 423 WP_003085219.1 OsmC family protein -
  CLH63_RS26465 (CLH63_26475) speD 5478914..5479708 (+) 795 WP_003101641.1 adenosylmethionine decarboxylase -
  CLH63_RS26470 (CLH63_26480) coq7 5479763..5480410 (-) 648 WP_003085224.1 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone monooxygenase -
  CLH63_RS26475 (CLH63_26485) - 5480510..5480848 (-) 339 WP_003085225.1 histidine triad nucleotide-binding protein -
  CLH63_RS26480 (CLH63_26490) - 5480927..5482408 (+) 1482 WP_003101642.1 AAA family ATPase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24225.01 Da        Isoelectric Point: 8.0525

>NTDB_id=205682 CLH63_RS26455 WP_003085214.1 5477256..5477900(-) (crp) [Pseudomonas aeruginosa strain CCUG 70744]
MVAITHTPKLKHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGDFFGELGLFEK
EGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEILYTLGSQMADRLRKTTRKVGDLAFLDVTGRVARTLLDLCQQPD
AMTHPDGMQIKITRQEIGRIVGCSREMVGRVLKSLEEQGLVHVKGKTMVVFGTR

Nucleotide


Download         Length: 645 bp        

>NTDB_id=205682 CLH63_RS26455 WP_003085214.1 5477256..5477900(-) (crp) [Pseudomonas aeruginosa strain CCUG 70744]
ATGGTAGCTATTACCCACACACCCAAACTCAAACACCTAGACAAGCTGCTCGCACACTGTCACCGCCGCCGCTACACCGC
AAAGAGCACCATCATCTATGCCGGCGATCGCTGCGAAACGCTGTTCTTCATCATCAAGGGTTCGGTCACCATCCTCATCG
AGGACGACGACGGCCGCGAAATGATCATCGGCTACCTCAACAGCGGTGATTTCTTCGGCGAGCTGGGATTGTTCGAAAAG
GAAGGCAGCGAACAGGAACGCAGCGCCTGGGTTCGCGCCAAGGTGGAATGCGAAGTCGCCGAGATCAGCTATGCGAAGTT
CCGCGAACTGTCGCAGCAGGACTCGGAGATCCTCTACACCCTCGGCAGCCAGATGGCCGACCGCCTGCGCAAGACCACCC
GCAAGGTGGGCGACCTGGCCTTCCTCGACGTCACCGGACGCGTCGCCCGCACCTTGCTGGACCTGTGCCAGCAACCGGAC
GCCATGACCCACCCGGACGGCATGCAGATCAAGATCACCCGCCAGGAGATCGGCCGGATCGTCGGCTGCTCGCGGGAAAT
GGTCGGACGCGTGCTGAAGAGCCTGGAGGAGCAGGGCCTGGTGCATGTGAAAGGAAAGACCATGGTGGTCTTCGGCACCC
GCTGA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(22-114)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(146-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZLY6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

67.327

94.393

0.636
  crp Haemophilus influenzae Rd KW20

60.396

94.393

0.57
  crp Acinetobacter baumannii D1279779

54.545

92.523

0.505

Multiple sequence alignment