Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CA696_RS03920 Genome accession   NZ_CP023142
Coordinates   748003..748662 (-) Length   219 a.a.
NCBI ID   WP_001221493.1    Uniprot ID   Q3YXL4
Organism   Escherichia coli strain CFSAN061770     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 743003..753662
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CA696_RS03895 (CA696_003895) - 743745..744692 (+) 948 WP_001305988.1 iron-siderophore ABC transporter substrate-binding protein -
  CA696_RS03900 (CA696_003900) - 744689..745576 (+) 888 WP_000614954.1 MurR/RpiR family transcriptional regulator -
  CA696_RS03905 (CA696_003905) ygiN 745621..745935 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  CA696_RS03910 (CA696_003910) mdaB 745966..746547 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  CA696_RS03915 (CA696_003915) qseC 746657..748006 (-) 1350 WP_000673375.1 quorum sensing histidine kinase QseC -
  CA696_RS03920 (CA696_003920) ciaR 748003..748662 (-) 660 WP_001221493.1 quorum sensing response regulator transcription factor QseB Regulator
  CA696_RS03925 (CA696_003925) ygiW 748814..749206 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  CA696_RS03930 (CA696_003930) ygiV 749259..749741 (+) 483 WP_024229347.1 GyrI-like domain-containing protein -
  CA696_RS03935 (CA696_003935) ygiS 749850..751457 (+) 1608 WP_095454363.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24687.63 Da        Isoelectric Point: 6.9850

>NTDB_id=205344 CA696_RS03920 WP_001221493.1 748003..748662(-) (ciaR) [Escherichia coli strain CFSAN061770]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=205344 CA696_RS03920 WP_001221493.1 748003..748662(-) (ciaR) [Escherichia coli strain CFSAN061770]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTATATAGTGCGCCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGTTAGCGGAACGTGTAGAGGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAACTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGCAGTGATTTTATTCGTACCGTTCATGGCATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3YXL4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365

Multiple sequence alignment