Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   JHP_RS00205 Genome accession   NC_000921
Coordinates   37867..38610 (+) Length   247 a.a.
NCBI ID   WP_000660577.1    Uniprot ID   Q9ZN26
Organism   Helicobacter pylori J99     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 32867..43610
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JHP_RS00180 (jhp0030) panD 35016..35369 (+) 354 WP_000142257.1 aspartate 1-decarboxylase -
  JHP_RS00185 (jhp0031) - 35372..35674 (+) 303 WP_000347931.1 YbaB/EbfC family nucleoid-associated protein -
  JHP_RS00190 (jhp0032) - 35674..36678 (+) 1005 WP_000468465.1 PDZ domain-containing protein -
  JHP_RS00195 (jhp0033) comB6 36686..37741 (+) 1056 WP_000679725.1 P-type conjugative transfer protein TrbL Machinery gene
  JHP_RS00200 comB7 37757..37870 (+) 114 WP_001217877.1 hypothetical protein Machinery gene
  JHP_RS00205 (jhp0034) comB8 37867..38610 (+) 744 WP_000660577.1 type IV secretion system protein Machinery gene
  JHP_RS00210 (jhp0035) comB9 38610..39596 (+) 987 WP_001878684.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  JHP_RS00215 (jhp0036) comB10 39589..40719 (+) 1131 WP_001045766.1 DNA type IV secretion system protein ComB10 Machinery gene
  JHP_RS00220 (jhp0037) - 40789..42201 (+) 1413 WP_000694964.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  JHP_RS00225 (jhp0038) gmd 42242..43387 (+) 1146 WP_000659868.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28710.95 Da        Isoelectric Point: 8.9891

>NTDB_id=20493 JHP_RS00205 WP_000660577.1 37867..38610(+) (comB8) [Helicobacter pylori J99]
MKEKPFNSEQMAFLEELLSHQEKHLESKLSGFSVNDLDMQSVFRLERNRLKIAYRLLGLMSFIALVLAIVLISILPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKAQNSIY
VQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLLNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRND

Nucleotide


Download         Length: 744 bp        

>NTDB_id=20493 JHP_RS00205 WP_000660577.1 37867..38610(+) (comB8) [Helicobacter pylori J99]
ATGAAAGAAAAGCCGTTCAATAGCGAGCAGATGGCTTTTTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAGAG
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTTCGGCTAGAAAGGAACCGCTTGAAAATCGCTT
ACAGGCTTTTAGGTTTGATGAGCTTTATCGCGCTTGTCTTAGCGATCGTTTTAATCAGTATCCTGCCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAATCGCATTGACGATAAATCCCGCT
ATGAACTGGTGCGCTTGCAAAGCAGCTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAGCCCAAAACAGCATCTAT
GTGCAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
GTCCATTGCGGCTAAACTTTTGAATGAAAACAAGCTCGTGTATGAAAAGCGTTATAAAATCGTATTGAGCTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GCGCCGACTAATAGGAATGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9ZN26

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

95.547

100

0.955

Multiple sequence alignment