Detailed information NTG0020491

Bioinformatically predicted

Overview

• Name: comB6
• Type: Machinery gene
• Locus tag: JHP_RS00195
• Genome accession: NC_000921
• Coordinates: 36686..37741 (+)
• Length: 351 a.a.
• NCBI ID: WP_000679725.1
• Uniprot ID: Q9ZN27
• Organism: Helicobacter pylori J99
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 31686..42741

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JHP_RS00165 (jhp0027)	-	32111..32524 (+)	414	WP_001023005.1	universal stress protein	-
JHP_RS00170 (jhp0028)	-	32526..32798 (+)	273	WP_000781796.1	ATP-dependent Clp protease adaptor ClpS	-
JHP_RS00175 (jhp0029)	-	32798..35026 (+)	2229	WP_000357196.1	AAA family ATPase	-
JHP_RS00180 (jhp0030)	panD	35016..35369 (+)	354	WP_000142257.1	aspartate 1-decarboxylase	-
JHP_RS00185 (jhp0031)	-	35372..35674 (+)	303	WP_000347931.1	YbaB/EbfC family nucleoid-associated protein	-
JHP_RS00190 (jhp0032)	-	35674..36678 (+)	1005	WP_000468465.1	PDZ domain-containing protein	-
JHP_RS00195 (jhp0033)	comB6	36686..37741 (+)	1056	WP_000679725.1	P-type conjugative transfer protein TrbL	Machinery gene
JHP_RS00200	comB7	37757..37870 (+)	114	WP_001217877.1	hypothetical protein	Machinery gene
JHP_RS00205 (jhp0034)	comB8	37867..38610 (+)	744	WP_000660577.1	type IV secretion system protein	Machinery gene
JHP_RS00210 (jhp0035)	comB9	38610..39596 (+)	987	WP_001878684.1	TrbG/VirB9 family P-type conjugative transfer protein	Machinery gene
JHP_RS00215 (jhp0036)	comB10	39589..40719 (+)	1131	WP_001045766.1	DNA type IV secretion system protein ComB10	Machinery gene
JHP_RS00220 (jhp0037)	-	40789..42201 (+)	1413	WP_000694964.1	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	-

Sequence

Protein

• Length: 351 a.a.
• Molecular weight: 39746.60 Da
• Isoelectric Point: 8.8294

>NTDB_id=20491 JHP_RS00195 WP_000679725.1 36686..37741(+) (comB6) [Helicobacter pylori J99]
MKHDAYEIILSWFITPLTAILGRFAEFFLYTLHAQLVFNSAVALAFMLFAYRSLKEQNFFSASALLEALWFVGFFALFNY
ALKNPSRFYELFQNAIFIAPNMITQSLSQSLSNFSNHALSLDFIFNHGFYALSFISDLSHNEMSVWLFLSILQALFLSVL
FAIIILVYLEAHVWCSLGALFLAFGFFKTWRSVVVICLKKCFALGFYKPFLLLVGFLNVSVTKALMDASMQEKQDLSLLL
VVALFLCCVFIIGVPFFINALFRVQNSLKETYKLATNLSANLTQSAFQSLQHATTSPAPSHISSSASQSVSKEKETHSPT
FKVETTQLDVKIPNFKQKKVKKDTIDTKNEI

Nucleotide

• Length: 1056 bp

>NTDB_id=20491 JHP_RS00195 WP_000679725.1 36686..37741(+) (comB6) [Helicobacter pylori J99]
ATGAAACATGACGCTTATGAAATCATTCTTTCTTGGTTTATCACGCCTCTCACAGCGATTTTAGGGCGTTTCGCTGAATT
TTTCCTCTACACCTTGCATGCGCAATTGGTGTTTAATAGCGCGGTCGCTTTGGCGTTCATGCTCTTTGCTTACAGGAGTT
TGAAAGAACAGAATTTTTTCAGTGCTAGCGCGCTTTTAGAAGCGTTATGGTTTGTGGGGTTTTTTGCGCTGTTTAACTAC
GCTTTGAAAAATCCTTCGCGCTTTTATGAATTGTTTCAAAACGCTATTTTTATTGCGCCTAACATGATCACTCAAAGCCT
TTCTCAAAGCTTGAGTAACTTTTCTAACCACGCGCTTTCTTTAGATTTTATTTTTAATCATGGTTTTTATGCCCTTAGCT
TCATTAGCGATTTGAGCCATAATGAAATGTCCGTGTGGCTTTTTTTAAGCATTTTGCAAGCGCTTTTTTTGAGCGTGCTG
TTTGCGATCATCATTTTAGTGTATTTGGAAGCGCATGTGTGGTGCTCTTTAGGGGCACTGTTTTTAGCGTTTGGGTTTTT
CAAAACCTGGAGGAGCGTTGTGGTTATATGCCTTAAAAAATGCTTCGCTCTTGGGTTTTACAAGCCTTTTTTGTTGTTAG
TGGGGTTTTTGAATGTGTCGGTTACTAAGGCGTTAATGGACGCTAGCATGCAAGAAAAACAAGACTTAAGCCTTTTATTG
GTGGTGGCGTTATTTTTGTGTTGCGTTTTTATCATCGGTGTGCCTTTTTTCATCAACGCTTTGTTTAGGGTGCAAAACAG
CCTTAAAGAAACTTACAAACTCGCCACCAATTTGAGCGCTAACCTCACTCAAAGCGCTTTCCAATCTTTACAGCATGCCA
CGACCTCGCCCGCTCCTTCTCATATTTCCTCTTCTGCAAGTCAAAGCGTTTCTAAAGAAAAGGAAACGCATTCCCCCACA
TTCAAGGTAGAAACCACTCAATTAGATGTAAAAATCCCAAATTTCAAGCAAAAAAAGGTTAAAAAGGATACAATAGATAC
AAAAAATGAAATTTAA

Domains

Predicted by InterproScan.

• TrbL/VirB6 plasmid conjugal transfer protein (TrbL) (44-254)

3D structure

• AlphaFold DB: Q9ZN27

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB6	Helicobacter pylori 26695	92.023	100	0.92