Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CJZ79_RS04415 Genome accession   NZ_CP022912
Coordinates   829318..829977 (-) Length   219 a.a.
NCBI ID   WP_001221493.1    Uniprot ID   Q3YXL4
Organism   Escherichia coli O6:H16 strain 2011EL-1370-2     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 824318..834977
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CJZ79_RS04385 parE 824409..826301 (+) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -
  CJZ79_RS04390 ygiN 826349..826663 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  CJZ79_RS04395 mdaB 826694..827275 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  CJZ79_RS04405 ygiZ 827594..827926 (+) 333 WP_000917686.1 DUF2645 family protein -
  CJZ79_RS04410 qseC 827972..829321 (-) 1350 WP_000673409.1 quorum sensing histidine kinase QseC -
  CJZ79_RS04415 ciaR 829318..829977 (-) 660 WP_001221493.1 quorum sensing response regulator transcription factor QseB Regulator
  CJZ79_RS04420 ygiW 830129..830521 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  CJZ79_RS04425 ygiV 830574..831056 (+) 483 WP_000183505.1 GyrI-like domain-containing protein -
  CJZ79_RS04430 mqsR 831260..831556 (+) 297 WP_000415584.1 type II toxin-antitoxin system toxin MqsR -
  CJZ79_RS04435 mqsA 831558..831953 (+) 396 WP_000650107.1 type II toxin-antitoxin system antitoxin MqsA -
  CJZ79_RS04440 ygiS 832086..833693 (+) 1608 WP_001295629.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24687.63 Da        Isoelectric Point: 6.9850

>NTDB_id=204581 CJZ79_RS04415 WP_001221493.1 829318..829977(-) (ciaR) [Escherichia coli O6:H16 strain 2011EL-1370-2]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=204581 CJZ79_RS04415 WP_001221493.1 829318..829977(-) (ciaR) [Escherichia coli O6:H16 strain 2011EL-1370-2]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGTT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3YXL4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365