Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   BG256_RS06940 Genome accession   NZ_CP017811
Coordinates   1404185..1404859 (+) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae strain NML-Hia-1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1399185..1409859
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BG256_RS06905 (BG256_06905) rpmG 1400102..1400272 (-) 171 WP_005613503.1 50S ribosomal protein L33 -
  BG256_RS06910 (BG256_06910) rpmB 1400284..1400520 (-) 237 WP_005542826.1 50S ribosomal protein L28 -
  BG256_RS06915 (BG256_06915) radC 1400734..1401399 (-) 666 WP_071163122.1 RadC family protein -
  BG256_RS06920 (BG256_06920) coaBC 1401562..1402764 (+) 1203 WP_071163123.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  BG256_RS06925 (BG256_06925) dut 1402812..1403267 (+) 456 WP_005631431.1 dUTP diphosphatase -
  BG256_RS06930 (BG256_06930) slmA 1403271..1403927 (+) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  BG256_RS06935 (BG256_06935) - 1403949..1404200 (+) 252 WP_005647999.1 YheU family protein -
  BG256_RS06940 (BG256_06940) crp 1404185..1404859 (+) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  BG256_RS06945 (BG256_06945) rlmC 1405224..1406402 (-) 1179 WP_071163124.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  BG256_RS06950 (BG256_06950) nagZ 1406399..1407451 (-) 1053 WP_071163125.1 beta-N-acetylhexosaminidase -
  BG256_RS06955 (BG256_06955) - 1407455..1407805 (-) 351 WP_005647993.1 YcfL family protein -
  BG256_RS06960 (BG256_06960) hinT 1407805..1408155 (-) 351 WP_005627389.1 purine nucleoside phosphoramidase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=203145 BG256_RS06940 WP_005647998.1 1404185..1404859(+) (crp) [Haemophilus influenzae strain NML-Hia-1]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=203145 BG256_RS06940 WP_005647998.1 1404185..1404859(+) (crp) [Haemophilus influenzae strain NML-Hia-1]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAGTATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42

Multiple sequence alignment