Detailed information    

insolico Bioinformatically predicted

Overview

Name   recD/recD2/recDB   Type   Machinery gene
Locus tag   Spy49_1439 Genome accession   CP000829
Coordinates   1444887..1447340 (+) Length   817 a.a.
NCBI ID   ACI61713.1    Uniprot ID   -
Organism   Streptococcus pyogenes NZ131     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1439887..1452340
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Spy49_1435c - 1442310..1442855 (-) 546 ACI61709.1 Conserved hypothetical protein -
  Spy49_1436c - 1442858..1443166 (-) 309 ACI61710.1 Conserved hypothetical protein -
  Spy49_1437 - 1443323..1444225 (+) 903 ACI61711.1 Ribonuclease HIII -
  Spy49_1438 spi 1444236..1444829 (+) 594 ACI61712.1 Putative signal peptidase I -
  Spy49_1439 recD/recD2/recDB 1444887..1447340 (+) 2454 ACI61713.1 Exodeoxyribonuclease V alpha chain Machinery gene
  Spy49_1440 - 1447431..1447913 (+) 483 ACI61714.1 Conserved hypothetical protein -
  Spy49_1441c dinP 1448006..1449100 (-) 1095 ACI61715.1 DNA polymerase IV -
  Spy49_1442 pfl 1449309..1451636 (+) 2328 ACI61716.1 Putative pyruvate formate-lyase -
  Spy49_1443c - 1451724..1452113 (-) 390 ACI61717.1 Putative esterase -

Sequence

Protein


Download         Length: 817 a.a.        Molecular weight: 91381.25 Da        Isoelectric Point: 4.6190

>NTDB_id=20295 Spy49_1439 ACI61713.1 1444887..1447340(+) (recD/recD2/recDB) [Streptococcus pyogenes NZ131]
MEYVFTGTVDRIIFENQANFFKILLLAIEDTDSDIDDFEIIITGTMADIIEGDDYTFWGELTQHPKYGQQLKLSRYQKIK
PSSSGLVNYFSSDHFKGIGKKTAEKIIALYGHNTIDHILEDPSKLETISGLSKANRQAFVAKLKLNYGTEQLIAGLVELG
LSNRFAFQAFEKYKEEALDLVKENPYQLVEDLQGFGFKMADALAENLGIESDSPKRFRAALLHCLLEESVSRGDTYVQAR
QLLDFAITLLEDARQVECDPAAVAEQLSELIIEGKIKNSDTKLFDASLYFAEEGIASNISRLLDTPLSQSFSHDTIQTTI
QAVQKDFAITYDQVQQEAITKALTSKVFLLTGGPGTGKTTVIRGILQAYANLHQIDLDKKDLPILLAAPTGRAARRMNEL
TGLPSATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLGAINSTTQVIIVGDSDQLPSVGPGQVLSDLL
KVNSLPQIALQKIFRQSQESTIVNLADQMRRGILAADFRDKKADRSYFEAQAAFIPDMIQKIVLSAIKSGIPAEEIQILA
PMYKGQAGINHLNQLMQELLNPLQGQTEFLFNDTHFRKGDKVLHLVNDAQLNVFNGDIGYITDLIPAKYTESKQDELILD
FDGSEVTYPRNEWLKLTLAYAMSIHKSQGSEFQVVILPITRQSGRLLQRNVIYTAITRSKSKLILLGEYSAFEYAIKHEG
DKRQTYLIERFQEQSDLASSQPNQELKSKEQTSLFSNTATLEDDSQKSSSQSTNSNPTENSQSDNDDFRLTPENYSTIDS
MIGLTESDIALFFQKKS

Nucleotide


Download         Length: 2454 bp        

>NTDB_id=20295 Spy49_1439 ACI61713.1 1444887..1447340(+) (recD/recD2/recDB) [Streptococcus pyogenes NZ131]
ATGGAATACGTTTTTACAGGTACTGTTGATCGTATCATTTTTGAAAACCAGGCTAATTTCTTTAAAATTCTCCTCCTTGC
CATTGAGGATACAGACAGTGACATTGACGACTTTGAAATCATTATCACAGGAACGATGGCTGACATTATTGAAGGAGATG
ACTACACCTTTTGGGGAGAATTGACCCAGCACCCTAAATATGGACAGCAACTCAAACTAAGCCGTTACCAAAAAATCAAA
CCTAGTTCATCTGGTTTGGTTAATTATTTCTCTAGTGACCATTTTAAGGGGATTGGTAAAAAAACAGCGGAGAAAATCAT
TGCGCTATATGGTCATAATACCATTGACCATATTTTAGAAGACCCAAGCAAATTAGAAACTATCTCTGGTCTGTCCAAGG
CTAATCGTCAAGCCTTTGTCGCTAAACTGAAATTGAATTATGGCACAGAGCAACTGATTGCTGGTCTCGTCGAACTTGGC
CTTAGCAACCGTTTTGCCTTTCAAGCGTTTGAGAAGTACAAAGAAGAGGCTCTTGACCTTGTTAAAGAAAATCCCTATCA
ATTAGTCGAAGATCTACAAGGTTTTGGGTTTAAGATGGCAGATGCTCTTGCTGAAAACTTAGGGATTGAGAGCGACTCTC
CAAAACGTTTTCGTGCTGCCCTCCTGCACTGCCTCTTGGAAGAATCCGTCAGTCGAGGAGACACTTATGTCCAAGCACGA
CAATTATTAGACTTTGCCATCACACTCCTTGAAGATGCACGTCAAGTAGAATGTGATCCTGCTGCTGTGGCTGAACAACT
AAGCGAGTTGATCATAGAGGGCAAAATCAAAAACAGTGACACCAAACTGTTTGATGCTAGCCTTTATTTTGCTGAAGAAG
GGATTGCTAGCAACATCTCTCGTCTCTTAGATACCCCTTTAAGTCAGTCATTTAGTCATGATACCATTCAAACAACCATC
CAAGCCGTTCAAAAAGACTTTGCCATCACCTATGACCAAGTGCAGCAAGAAGCCATTACTAAGGCCTTAACCAGCAAGGT
CTTTCTCCTAACAGGTGGTCCCGGAACAGGAAAAACAACTGTTATTCGAGGCATTTTGCAGGCTTACGCGAACCTGCATC
AGATTGATTTGGATAAAAAAGACCTTCCTATCTTGTTAGCAGCTCCAACAGGTCGAGCTGCACGTCGCATGAATGAGTTG
ACTGGACTTCCTAGCGCAACCATCCACAGGCACTTAGGCCTCAATGGCGACAACGATTACCAAGCCATGGAGGATTATCT
AGACTGCGACCTGCTGATTGTCGATGAATTTTCAATGGTGGATACCTGGCTTGCCAACCAGTTGTTAGGAGCGATTAACT
CAACAACTCAAGTGATTATTGTCGGAGATAGTGACCAGCTTCCTTCGGTTGGACCCGGTCAAGTCCTGTCAGATCTTTTA
AAAGTCAATAGCCTGCCCCAAATCGCCTTGCAAAAGATATTTCGTCAATCCCAAGAATCTACTATTGTCAATTTGGCAGA
CCAGATGCGTCGAGGAATCTTAGCTGCTGACTTTCGTGATAAAAAAGCTGACCGTTCTTATTTTGAAGCCCAAGCAGCCT
TTATCCCTGACATGATTCAAAAAATTGTCCTATCTGCCATTAAAAGTGGCATCCCTGCTGAGGAAATTCAAATTTTAGCG
CCTATGTACAAAGGACAAGCTGGCATCAATCATCTTAATCAACTCATGCAAGAACTTCTCAATCCCTTGCAAGGACAAAC
AGAATTTCTGTTCAATGATACGCATTTTCGTAAAGGTGATAAAGTCTTGCACTTAGTCAACGATGCTCAGTTGAATGTCT
TTAACGGAGATATTGGTTATATTACAGATTTGATTCCTGCTAAATATACCGAATCTAAGCAAGACGAATTAATCTTAGAT
TTTGACGGTAGCGAAGTCACGTACCCTAGAAATGAATGGCTAAAATTAACCCTGGCCTATGCCATGAGCATTCATAAGTC
ACAAGGGAGCGAGTTTCAAGTGGTGATTTTACCTATCACACGCCAAAGCGGCCGACTCTTGCAACGAAATGTGATTTACA
CGGCCATTACTCGGTCTAAAAGTAAGTTAATTCTGTTGGGAGAATATTCTGCCTTTGAGTATGCTATTAAACACGAAGGC
GATAAACGCCAAACCTACTTGATCGAACGCTTCCAAGAACAATCCGACTTAGCCTCCTCTCAACCTAACCAAGAGCTAAA
ATCAAAAGAGCAGACCTCCCTTTTTTCTAATACGGCAACCCTTGAGGACGACTCTCAAAAATCTTCCTCTCAATCAACAA
ACTCTAACCCCACTGAGAACTCTCAGTCAGATAATGATGATTTTAGGTTAACACCTGAGAATTATTCGACTATCGATTCG
ATGATAGGGCTTACAGAATCAGATATTGCCCTCTTTTTCCAGAAAAAATCCTAG

Domains

Predicted by InterProScan.

Helix-hairpin-helix containing domain (HHH_RecD2)

(147-236)

UvrD-like helicase C-terminal domain (UvrD_C_2)

(659-706)

AAA domain (AAA_30)

(331-522)

ATP-dependent RecD-like DNA helicase SH3 domain (SH3_13)

(572-641)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recD/recD2/recDB Bacillus subtilis subsp. subtilis str. 168

41.91

92.289

0.387

Multiple sequence alignment