Detailed information NTG0020277

Bioinformatically predicted

Overview

• Name: comFA/cflA
• Type: Machinery gene
• Locus tag: DN94_00565
• Genome accession: CP007565
• Coordinates: 100174..101463 (+)
• Length: 429 a.a.
• NCBI ID: AHX74312.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain 138spar
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 95174..106463

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DN94_00530	-	95402..96157 (+)	756	AHX74307.1	DeoR faimly transcriptional regulator	-
DN94_00540	-	97463..97786 (+)	324	AHX74308.1	PTS cellobiose transporter subunit IIA	-
DN94_00545	-	97803..98108 (+)	306	AHX74309.1	cytochrome C biogenesis protein CcmE	-
DN94_00550	-	98110..98274 (+)	165	AHX74310.1	PTS system, cellobiose-specific IIC component	-
DN94_00560	-	99474..100118 (-)	645	AHX74311.1	Xaa-Pro dipeptidase	-
DN94_00565	comFA/cflA	100174..101463 (+)	1290	AHX74312.1	competence protein	Machinery gene
DN94_00575	-	102204..102764 (+)	561	AHX74313.1	ribosome-associated factor Y	-

Sequence

Protein

• Length: 429 a.a.
• Molecular weight: 48671.48 Da
• Isoelectric Point: 9.9941

>NTDB_id=20277 DN94_00565 AHX74312.1 100174..101463(+) (comFA/cflA) [Streptococcus agalactiae strain 138spar]
MENYLGRLWTKAQLSEQLRKIAISLPSFIKKGSDYICTRCSSSVAKNCQLPTGNYYCRECIVFGRVTSNENLYYFPQKTF
SKTNSLKWKGGLTPYQNEVSEELLKGISSKENLLVHAVTGAGKTEMIYHSVAKVIDTGGSVCIASPRIDVCLELHKRLSN
DFRCAITLMHGESPSYQRSPLTIATTHQLLKFYHAFDLLIVDEVDAFPYVDNPILYHGVKQALKENGTSIFLTATSTTEL
ERKVARKELKKLHLARRFHANPLVIPEMVWVSGIQKSLQTQKLPPKLYQLINKQRQTRYPLLLFFPHISEGQVFTEILRQ
AFPMEKIGFVSSKSTSRLKLVQDFRDNKLSILVSTTILERGVTFPSVDVFVIQANHHLFTKSSLVQISGRVGRALERPEG
LLYFLHDGKSKSMHQAIKEIKNMNHIGGF

Nucleotide

• Length: 1290 bp

>NTDB_id=20277 DN94_00565 AHX74312.1 100174..101463(+) (comFA/cflA) [Streptococcus agalactiae strain 138spar]
ATGGAAAATTATTTAGGTAGGCTTTGGACAAAAGCACAATTATCTGAGCAACTTAGAAAAATTGCAATTAGCTTGCCATC
TTTTATAAAGAAAGGAAGCGACTATATTTGTACTCGATGCTCTAGTTCTGTTGCTAAAAATTGCCAATTACCAACTGGAA
ATTATTATTGTAGAGAATGTATAGTTTTTGGAAGAGTTACTAGTAATGAAAATTTATATTATTTTCCACAAAAAACATTT
TCTAAAACGAATTCTTTAAAATGGAAAGGGGGACTGACACCTTATCAAAATGAGGTTTCAGAAGAGTTGTTGAAAGGTAT
TTCAAGTAAGGAAAATCTTCTTGTTCATGCTGTGACAGGGGCTGGTAAAACAGAAATGATATACCACTCTGTCGCCAAAG
TAATTGATACTGGAGGAAGCGTTTGTATTGCCAGTCCTAGAATTGATGTTTGTTTAGAATTGCATAAGCGACTTTCAAAC
GATTTTAGATGTGCCATAACATTAATGCATGGAGAATCTCCTTCTTATCAGAGATCCCCTTTAACTATTGCCACAACACA
TCAATTGTTAAAATTTTATCATGCTTTTGATTTGCTAATTGTTGATGAAGTTGATGCTTTTCCATATGTCGACAACCCGA
TACTATACCATGGTGTAAAACAGGCTTTAAAGGAAAACGGAACAAGTATTTTTCTGACTGCAACTTCAACGACTGAGTTA
GAAAGAAAAGTTGCAAGAAAAGAACTAAAAAAATTGCATCTAGCTAGGAGATTTCATGCCAATCCGTTAGTGATACCCGA
GATGGTTTGGGTAAGTGGTATCCAGAAAAGCTTGCAGACACAAAAACTACCTCCCAAATTATATCAGCTGATAAATAAAC
AGCGACAAACGAGATATCCTTTGTTATTATTTTTCCCCCATATTTCAGAAGGTCAGGTATTCACCGAAATTTTAAGACAA
GCCTTTCCTATGGAAAAAATTGGTTTTGTTTCAAGTAAGAGCACATCTAGGTTAAAGTTAGTGCAAGATTTTCGAGATAA
CAAATTGTCTATCCTAGTGTCAACTACTATTCTAGAGAGAGGAGTAACTTTCCCTAGCGTCGACGTTTTTGTTATACAAG
CAAATCATCATTTGTTTACGAAAAGTTCCTTGGTACAAATTTCAGGAAGAGTTGGAAGAGCATTAGAAAGGCCCGAAGGG
CTCCTTTACTTCCTTCATGATGGGAAAAGTAAATCAATGCATCAAGCTATAAAGGAGATTAAAAACATGAATCATATAGG
AGGATTTTAA

Domains

Predicted by InterproScan.

• Helicase conserved C-terminal domain (Helicase_C) (286-394)

• DEAD/DEAH box helicase (DEAD) (93-240)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFA/cflA	Streptococcus mitis NCTC 12261	60.89	99.534	0.606
comFA/cflA	Streptococcus pneumoniae Rx1	60.422	99.534	0.601
comFA/cflA	Streptococcus pneumoniae D39	60.422	99.534	0.601
comFA/cflA	Streptococcus pneumoniae R6	60.422	99.534	0.601
comFA/cflA	Streptococcus mitis SK321	60.422	99.534	0.601
comFA/cflA	Streptococcus pneumoniae TIGR4	60.422	99.534	0.601
comFA	Lactococcus lactis subsp. cremoris KW2	50	91.841	0.459
comFA	Bacillus subtilis subsp. subtilis str. 168	39.312	94.872	0.373
comFA	Latilactobacillus sakei subsp. sakei 23K	36.322	100	0.368