Detailed information NTG0020248

Bioinformatically predicted

Overview

• Name: comD/comD1
• Type: Regulator
• Locus tag: SPG_2184
• Genome accession: CP001015
• Coordinates: 2074525..2075850 (-)
• Length: 441 a.a.
• NCBI ID: ACF56316.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae G54
• Function: phosphorylation of ComE (predicted from homology) Competence regulation

Genomic Context

Location: 2069525..2080850

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPG_2178	-	2071622..2071960 (-)	339	ACF54773.1	conserved hypothetical protein	-
SPG_2179	-	2072045..2072812 (-)	768	ACF56436.1	hypothetical protein	-
SPG_2180	-	2072991..2073533 (+)	543	ACF56205.1	conserved hypothetical protein	-
SPG_2183	comE	2073776..2074528 (-)	753	ACF55408.1	ComE response regulator TCS12	Regulator
SPG_2184	comD/comD1	2074525..2075850 (-)	1326	ACF56316.1	ComD histidine kinase TCS12	Regulator
SPG_2185	comC/comC1	2075871..2075996 (-)	126	ACF56795.1	competence-stimulating peptide type 1, CSP1	Regulator
SPG_2187	-	2076278..2076757 (-)	480	ACF55146.1	conserved hypothetical protein	-
SPG_2188	htrA	2076940..2078121 (+)	1182	ACF55645.1	serine protease	Regulator
SPG_2189	spo0J	2078179..2078937 (+)	759	ACF55136.1	ParB-like partition protein	Regulator

Sequence

Protein

• Length: 441 a.a.
• Molecular weight: 51387.56 Da
• Isoelectric Point: 6.6400

>NTDB_id=20248 SPG_2184 ACF56316.1 2074525..2075850(-) (comD/comD1) [Streptococcus pneumoniae G54]
MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTEIVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQY
ERDRGLFLSLLLSLLYESTHNFLSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIALKQKKFEQKHLQNYTDEIVGLY
NEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEVLVKXNHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEF
TLEVKDTITKLPIELLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVVVIQNSCKMTMTPSGDLFALGFSTKGR
NRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE

Nucleotide

• Length: 1326 bp

>NTDB_id=20248 SPG_2184 ACF56316.1 2074525..2075850(-) (comD/comD1) [Streptococcus pneumoniae G54]
ATGGATTTATTTGGATTTGGGACGGTTATTGTTCATTTTTTAATTATTAGTCACAGTTACCATTTTATTTGTAAAGGTCA
AATAAATAGAAAAGAATTATTCGTTTTTGGTGCTTATACATTACTAACAGAAATAGTATTTGATTTTCCCTTATATATTC
TATATTTAGATGGGTTAGGGATTGAAAGATTTTTATTTCCTTTGGGATTATATTCCTATTTTCGATGGATGAAACAGTAT
GAGAGGGATAGAGGACTATTCCTAAGTTTACTACTATCTCTTTTATATGAGAGCACTCATAACTTTCTGTCCGTAACTTT
CTCCTCTATAACAGGAGATAATTTTGTTTTACAATATCATTTCCCATTCTTTTTCGTTGTGACGGTGTTAACCTATTTTG
TTACATTAAAAATCATTTACTATTTCCATTTGGAACTAGCCTATTTTGACGAGGACTACCTTTATCCTTTCTTGAAAAAA
GTATTTTTTGCTTTACTATTGCTACATATTGTATCTTTCGTTTCAGATATGGTAAGTACGATTAAACATTTGAATAGTTT
TGGAAGTATTTTGTCATCTATTGTCTTTATCTCTCTCCTTTTGACCTTCTTTGCAATGAATTCTCATAAAGTTCAAATGG
AGAAAGAGATTGCTTTGAAGCAGAAGAAATTTGAACAGAAACATTTACAGAATTACACAGATGAAATTGTTGGTCTGTAT
AATGAAATCCGTGGTTTTCGACATGATTATGCTGGAATGCTTGTCAGCATGCAGATGGCAATTGACAGTGGTAATTTACA
GGAAATTGACAGAATTTACAATGAAGTTTTAGTCAAANCNAATCATAAATTGCGTTCAGATAAGTACACTTACTTTGATT
TGAACAACATAGAAGACTCAGCTTTACGAAGTTTGGTTGCTCAGTCAATTGTCTATGCTCGAAATAATGGTGTAGAGTTT
ACACTGGAAGTAAAAGATACGATTACCAAGCTTCCAATTGAACTATTGGATTTGGTTCGTATCATGAGCGTTTTATTGAA
TAATGCTGTCGAAGGATCGGCTGATAGCTATAAAAAGCAGATGGAAGTAGCAGTTATTAAGATGGAAACTGAAACAGTTG
TTGTGATTCAGAATTCATGTAAAATGACGATGACTCCTTCAGGAGATCTATTTGCCTTAGGATTCTCCACTAAGGGAAGA
AATCGCGGAGTCGGATTAAATAATGTGAAAGAACTACTAGATAAGTACAACAATATTATTTTAGAAACAGAGATGGAAGG
CAGTACATTTAGACAAATCATTAGATTTAAGAGGGAATTTGAATGA

Domains

Predicted by InterproScan.

• GHKL domain (HATPase_c_5) (334-434)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comD/comD1	Streptococcus pneumoniae Rx1	99.546	100	0.995
comD/comD1	Streptococcus pneumoniae D39	99.546	100	0.995
comD/comD1	Streptococcus pneumoniae R6	99.546	100	0.995
comD/comD2	Streptococcus pneumoniae TIGR4	96.372	100	0.964
comD	Streptococcus mitis SK321	91.61	100	0.916
comD	Streptococcus mitis NCTC 12261	85.714	100	0.857
comD/comD2	Streptococcus gordonii strain NCTC7865	49.202	85.261	0.42
comD/comD1	Streptococcus gordonii str. Challis substr. CH1	49.465	84.807	0.419