Detailed information NTG0202387

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: CHY23_RS05370
• Genome accession: NZ_CP022715
• Coordinates: 1080152..1080826 (-)
• Length: 224 a.a.
• NCBI ID: WP_005599747.1
• Uniprot ID: -
• Organism: Actinobacillus pleuropneumoniae strain KL 16
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1075152..1085826

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CHY23_RS05340 (CHY23_01074)	adhP	1075254..1076303 (+)	1050	WP_005602862.1	alcohol dehydrogenase AdhP	-
CHY23_RS05345 (CHY23_01075)	miaA	1076435..1077379 (+)	945	WP_005618608.1	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	-
CHY23_RS05350 (CHY23_01076)	hfq	1077444..1077722 (+)	279	WP_005599741.1	RNA chaperone Hfq	-
CHY23_RS05355 (CHY23_01077)	hflX	1077904..1079121 (+)	1218	WP_005599743.1	ribosome rescue GTPase HflX	-
CHY23_RS05360 (CHY23_01078)	-	1079157..1079717 (-)	561	WP_005599745.1	TIGR00730 family Rossman fold protein	-
CHY23_RS05365 (CHY23_01079)	-	1079780..1080103 (+)	324	WP_005599746.1	MazG nucleotide pyrophosphohydrolase domain-containing protein	-
CHY23_RS05370 (CHY23_01080)	crp	1080152..1080826 (-)	675	WP_005599747.1	cAMP-activated global transcriptional regulator CRP	Regulator
CHY23_RS05375 (CHY23_01081)	-	1080904..1081122 (-)	219	WP_005599748.1	YheU family protein	-
CHY23_RS05380 (CHY23_01083)	slmA	1081128..1081735 (-)	608	Protein_1016	nucleoid occlusion factor SlmA	-
CHY23_RS05385 (CHY23_01084)	dut	1081841..1082296 (-)	456	WP_005599752.1	dUTP diphosphatase	-
CHY23_RS05390 (CHY23_01085)	coaBC	1082305..1083510 (-)	1206	WP_005602882.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
CHY23_RS05395 (CHY23_01086)	radC	1083718..1084380 (+)	663	WP_005599756.1	RadC family protein	Machinery gene
CHY23_RS05400 (CHY23_01087)	rpmB	1084549..1084785 (+)	237	WP_005599762.1	50S ribosomal protein L28	-
CHY23_RS05405 (CHY23_01088)	rpmG	1084797..1084967 (+)	171	WP_005599764.1	50S ribosomal protein L33	-
CHY23_RS11335 (CHY23_01089)	-	1085093..1085311 (+)	219	WP_162031030.1	hypothetical protein	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25147.02 Da
• Isoelectric Point: 6.5834

>NTDB_id=202387 CHY23_RS05370 WP_005599747.1 1080152..1080826(-) (crp) [Actinobacillus pleuropneumoniae strain KL 16]
MQDISISTPQLDSELSAPSIHDPAVEWFLTHCHIHRYPSKYTLIHAGEDAESLFYIVSGSVAVFIKDEEGKEMILSHLGQ
GEFVGEISLFEDTIQPRTAWVKTKGACEIAEISYKKFKQLVHLNPDILMYLSAQMARRLRQTSRQVSNLAFLDVTGRIAQ
TLMNLAKMPDAMTHPEGMQIKITRQEIGQMVGCSRETVGRILKMLEDEGLISAHGKTIVVYGTR

Nucleotide

• Length: 675 bp

>NTDB_id=202387 CHY23_RS05370 WP_005599747.1 1080152..1080826(-) (crp) [Actinobacillus pleuropneumoniae strain KL 16]
ATGCAAGATATTTCAATTTCAACACCTCAGCTAGACAGTGAGCTGTCCGCCCCGTCTATTCATGATCCGGCGGTGGAATG
GTTTCTGACTCACTGTCATATTCATCGTTATCCGTCAAAATATACGCTTATTCATGCGGGTGAGGATGCCGAATCATTAT
TCTATATCGTCAGCGGCTCCGTTGCAGTGTTTATTAAAGATGAAGAAGGGAAAGAAATGATCCTTTCTCACCTCGGTCAA
GGTGAATTTGTCGGTGAAATCAGCTTATTTGAAGACACTATTCAACCGCGTACCGCTTGGGTCAAAACCAAAGGCGCTTG
CGAAATTGCGGAAATCTCGTATAAAAAATTCAAACAGCTTGTGCATTTAAATCCGGATATTCTTATGTATCTTTCCGCGC
AAATGGCTCGCCGCCTACGCCAAACCTCACGCCAAGTAAGTAACCTCGCTTTCTTAGACGTAACCGGTCGTATCGCACAA
ACCTTAATGAATTTGGCGAAAATGCCGGATGCGATGACCCATCCGGAAGGAATGCAAATTAAGATTACCCGCCAAGAAAT
CGGTCAAATGGTCGGTTGTTCTCGAGAAACGGTCGGTAGAATCTTAAAAATGCTAGAAGATGAAGGCTTAATTTCAGCAC
ACGGTAAAACCATTGTCGTTTATGGCACTCGCTAA

Domains

Predicted by InterProScan.

• Crp-like helix-turn-helix domain (HTH_Crp_2) (156-220)

• Cyclic nucleotide-binding domain (cNMP_binding) (36-121)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Vibrio cholerae strain A1552	77.34	90.625	0.701
crp	Haemophilus influenzae Rd KW20	73.892	90.625	0.67
crp	Acinetobacter baumannii D1279779	45.794	95.536	0.437