Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   RM34_RS13530 Genome accession   NZ_CP022689
Coordinates   2558257..2558889 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain CDC#03-98     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2553257..2563889
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RM34_RS13505 (RM34_13505) yhfG 2553389..2553556 (+) 168 WP_000736862.1 YhfG family protein -
  RM34_RS13510 (RM34_13510) fic 2553546..2554148 (+) 603 WP_001280650.1 putative adenosine monophosphate-protein transferase Fic -
  RM34_RS13515 (RM34_13515) pabA 2554180..2554743 (+) 564 WP_000601867.1 aminodeoxychorismate synthase component 2 -
  RM34_RS13520 (RM34_13520) argD 2554829..2556049 (+) 1221 WP_000963819.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  RM34_RS13525 (RM34_13525) yhfK 2556116..2558206 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  RM34_RS13530 (RM34_13530) crp 2558257..2558889 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  RM34_RS13540 (RM34_13540) yhfA 2559191..2559595 (+) 405 WP_001148908.1 OsmC family protein -
  RM34_RS13545 (RM34_13545) prkB 2559650..2560519 (-) 870 WP_001274677.1 phosphoribulokinase -
  RM34_RS13550 (RM34_13550) yheU 2560573..2560791 (-) 219 WP_000907085.1 YheU family protein -
  RM34_RS13555 (RM34_13555) yheT 2560785..2561807 (-) 1023 WP_000057377.1 hydrolase -
  RM34_RS13560 (RM34_13560) yheS 2561807..2563720 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=202247 RM34_RS13530 WP_000242755.1 2558257..2558889(-) (crp) [Escherichia coli strain CDC#03-98]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=202247 RM34_RS13530 WP_000242755.1 2558257..2558889(-) (crp) [Escherichia coli strain CDC#03-98]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCTGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTCAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment