Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CIW80_RS11245 Genome accession   NZ_CP022686
Coordinates   2226114..2226746 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli Nissle 1917     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2221114..2231746
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CIW80_RS11215 (CIW80_11295) yheS 2221283..2223196 (+) 1914 WP_000634808.1 ABC transporter ATP-binding protein -
  CIW80_RS11220 (CIW80_11300) yheT 2223196..2224218 (+) 1023 WP_000057387.1 hydrolase -
  CIW80_RS11225 (CIW80_11305) yheU 2224212..2224430 (+) 219 WP_000907085.1 YheU family protein -
  CIW80_RS11230 (CIW80_11310) prkB 2224484..2225353 (+) 870 WP_001274684.1 phosphoribulokinase -
  CIW80_RS11235 (CIW80_11315) yhfA 2225408..2225812 (-) 405 WP_001148908.1 OsmC family protein -
  CIW80_RS11245 (CIW80_11325) crp 2226114..2226746 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CIW80_RS11250 (CIW80_11330) yhfK 2226797..2228887 (+) 2091 WP_001304921.1 YccS/YhfK family putative transporter -
  CIW80_RS11255 (CIW80_11335) argD 2228954..2230174 (-) 1221 WP_000963800.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CIW80_RS11260 (CIW80_11340) pabA 2230260..2230823 (-) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  CIW80_RS11265 (CIW80_11345) fic 2230855..2231457 (-) 603 WP_001280638.1 putative adenosine monophosphate-protein transferase Fic -
  CIW80_RS11270 (CIW80_11350) yhfG 2231447..2231614 (-) 168 WP_000736858.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=202151 CIW80_RS11245 WP_000242755.1 2226114..2226746(+) (crp) [Escherichia coli Nissle 1917]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=202151 CIW80_RS11245 WP_000242755.1 2226114..2226746(+) (crp) [Escherichia coli Nissle 1917]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467