Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CG712_RS03200 Genome accession   NZ_CP022547
Coordinates   617039..617683 (-) Length   214 a.a.
NCBI ID   WP_002951384.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain B59671     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 612039..622683
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CG712_RS03175 (CG712_03205) - 614141..615138 (-) 998 Protein_621 NAD(P)/FAD-dependent oxidoreductase -
  CG712_RS03180 (CG712_03210) trmD 615140..615859 (-) 720 WP_011226285.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  CG712_RS03185 (CG712_03215) rimM 615849..616367 (-) 519 WP_011226286.1 ribosome maturation factor RimM -
  CG712_RS03200 (CG712_03230) vraR 617039..617683 (-) 645 WP_002951384.1 response regulator transcription factor Regulator
  CG712_RS03205 (CG712_03235) - 617673..618683 (-) 1011 WP_011226288.1 sensor histidine kinase -
  CG712_RS03210 (CG712_03240) liaF 618680..619378 (-) 699 WP_011226289.1 cell wall-active antibiotics response protein LiaF -
  CG712_RS10185 - 619633..619800 (-) 168 WP_232510045.1 ion channel -
  CG712_RS03220 (CG712_03250) stkP/pknB 620437..622308 (-) 1872 WP_096811563.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24048.39 Da        Isoelectric Point: 4.5864

>NTDB_id=201595 CG712_RS03200 WP_002951384.1 617039..617683(-) (vraR) [Streptococcus thermophilus strain B59671]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=201595 CG712_RS03200 WP_002951384.1 617039..617683(-) (vraR) [Streptococcus thermophilus strain B59671]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGACCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTCAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCATGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379

Multiple sequence alignment