Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   BKM66_RS07045 Genome accession   NZ_CP017666
Coordinates   1434587..1435936 (-) Length   449 a.a.
NCBI ID   WP_002935841.1    Uniprot ID   G7SGQ2
Organism   Streptococcus suis strain 0061     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1429587..1440936
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BKM66_RS07030 (BKM66_06855) pbp2b 1429974..1432043 (-) 2070 WP_014637681.1 penicillin-binding protein PBP2B -
  BKM66_RS07035 (BKM66_06860) vga(F) 1432135..1433520 (-) 1386 WP_014637680.1 ABC-F type ribosomal protection protein Vga(F) -
  BKM66_RS07040 (BKM66_06865) vicX 1433777..1434580 (-) 804 WP_044681030.1 MBL fold metallo-hydrolase Regulator
  BKM66_RS07045 (BKM66_06870) micB 1434587..1435936 (-) 1350 WP_002935841.1 cell wall metabolism sensor histidine kinase VicK Regulator
  BKM66_RS07050 (BKM66_06875) micA 1435929..1436633 (-) 705 WP_004298854.1 response regulator YycF Regulator
  BKM66_RS07055 (BKM66_06880) - 1436827..1437588 (+) 762 WP_024399907.1 amino acid ABC transporter ATP-binding protein -
  BKM66_RS07060 (BKM66_06885) - 1437599..1438438 (+) 840 WP_014637678.1 transporter substrate-binding domain-containing protein -
  BKM66_RS07065 (BKM66_06890) - 1438453..1439151 (+) 699 WP_014637677.1 amino acid ABC transporter permease -
  BKM66_RS07070 (BKM66_06895) - 1439166..1439825 (+) 660 WP_014637676.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51039.08 Da        Isoelectric Point: 4.5202

>NTDB_id=201311 BKM66_RS07045 WP_002935841.1 1434587..1435936(-) (micB) [Streptococcus suis strain 0061]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSSQKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=201311 BKM66_RS07045 WP_002935841.1 1434587..1435936(-) (micB) [Streptococcus suis strain 0061]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAACGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGACATGGCGAATTCTCTTAATGATCTGTCCGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACGCGTCTGACTTCCATCTTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGCTTTCTAGCCAAAAGC
AGGAGCAGTATCACCTGCTCGAGGTTTTAGATTTATCAGATCGTTACACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTCTGACTTTACGCGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCTTGGTTGTCGTCTTACATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTCAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTAACG
GAGTCTGTTGCACCGAGTTTTGTTAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTAAG
TTTATCGCGCATTGATAATCAGGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCTGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTGGATAATATCTTAAATAATGCCATTAAATATTCGCCAGACGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTGTCCGTCTCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTCTATCGCGTGGACAAGGCACGATCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTAAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(96-199)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SGQ2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.183

97.105

0.682
  vicK Streptococcus mutans UA159

70.72

89.755

0.635

Multiple sequence alignment