Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SSU05_0437 Genome accession   CP000407
Coordinates   417839..419134 (+) Length   431 a.a.
NCBI ID   ABP89404.1    Uniprot ID   -
Organism   Streptococcus suis 05ZYH33     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 412839..424134
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSU05_0431 - 413189..413281 (+) 93 ABP89397.1 hypothetical protein -
  SSU05_0432 - 413645..414136 (+) 492 ABP89399.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain -
  SSU05_0433 - 414338..415738 (+) 1401 ABP89400.1 Predicted hydrolase of the HAD superfamily -
  SSU05_0434 - 415740..416111 (+) 372 ABP89401.1 Predicted RNA binding protein (contains ribosomal protein S1 domain) -
  SSU05_0435 - 416137..417111 (-) 975 ABP89402.1 O-acetylserine lyase -
  SSU05_0436 - 417153..417791 (-) 639 ABP89403.1 Uncharacterized conserved protein -
  SSU05_0437 comFA/cflA 417839..419134 (+) 1296 ABP89404.1 Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) Machinery gene
  SSU05_0438 comFC/cflB 419127..419792 (+) 666 ABP89405.1 Predicted amidophosphoribosyltransferase Machinery gene
  SSU05_0439 - 419833..420411 (+) 579 ABP89406.1 Ribosome-associated protein Y (PSrp-1) -

Sequence

Protein


Download         Length: 431 a.a.        Molecular weight: 49106.79 Da        Isoelectric Point: 9.0603

>NTDB_id=20080 SSU05_0437 ABP89404.1 417839..419134(+) (comFA/cflA) [Streptococcus suis 05ZYH33]
MMKELENYYGRLFTKYQLTAKEREIAEKVPSITKKNNCFRCGTTFEEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKD
FPITKCLKWKGQLTDWQQRISDGLVANVENNRATLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQ
NDFSVPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYRAADNAVKEAGVQVFLTATSTDE
LDKKVRTGKLSRLSLPRRFHGNPLVVPQKVWFSKFDDTLKKNRLVPKLKKAIEEQRKSCFPLLIFVPEISKGQEFTKIMK
KTFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLYTVSSLVQIAGRVGRSMERPT
GLLQFYHEGSTGAIEKAVAEIKQMNKEAGYV

Nucleotide


Download         Length: 1296 bp        

>NTDB_id=20080 SSU05_0437 ABP89404.1 417839..419134(+) (comFA/cflA) [Streptococcus suis 05ZYH33]
GTGATGAAAGAATTAGAAAATTATTATGGAAGATTATTTACCAAATACCAATTGACAGCAAAAGAAAGAGAAATAGCAGA
AAAAGTGCCAAGTATTACAAAAAAGAATAACTGCTTTCGCTGTGGAACAACTTTTGAAGAAGAAAACAAATTGCCAAACG
ATGCTTATTACTGTCGAGCCTGCTTGCTTCTAGGCAGAGTACGGTCAGACGAAAAACTCTATCATTTTCCTCAGAAAGAT
TTTCCAATCACTAAGTGTTTAAAGTGGAAAGGTCAATTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAA
CGTGGAAAATAATCGTGCGACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATCTACCACACCGTTGCCT
CAGTGATTGATAAAGGCGGAGCGGTTTGCCTAGCCAGTCCTCGAATTGATGTTTGTATCGAACTCTATAAACGTCTGCAA
AATGACTTTTCAGTTCCAATTAGTTTACTACATGGAGAGTCTGAACCCTATTTCCGAACCCCATTAGTTGTAGCAACCAC
ACATCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCAGATAATC
CCATGCTCTATCGAGCAGCAGACAATGCGGTCAAGGAAGCTGGTGTTCAAGTTTTTCTGACAGCGACTTCAACAGATGAA
TTGGATAAAAAAGTCAGAACAGGTAAATTAAGTCGTCTTAGTTTGCCAAGGCGCTTTCATGGCAACCCACTTGTTGTCCC
GCAAAAAGTCTGGTTTAGTAAATTCGATGATACCCTAAAGAAAAATAGACTAGTTCCAAAGTTGAAAAAAGCGATTGAAG
AACAGAGAAAGTCGTGCTTTCCCTTACTCATTTTTGTCCCAGAAATCTCCAAAGGTCAAGAATTTACCAAGATAATGAAA
AAAACATTCCCAGAAGAAACAATTGGCTTTGTATCCAGTCAAACAGAAAATCGCCTTGAAATAGTTGAAGGGTTTCGCAA
GAGAGAAATCACAGTCTTAATCTCGACTACTATTCTTGAACGTGGGGTGACCTTCCCATGTGTAGACGTCTTTGTTGTTC
AAGCCAATCATTACCTCTACACAGTGTCAAGTCTTGTTCAGATTGCAGGCCGAGTCGGAAGGAGTATGGAACGTCCGACT
GGTTTACTCCAGTTTTATCATGAGGGAAGTACAGGAGCCATTGAAAAGGCAGTCGCTGAAATTAAACAGATGAACAAGGA
GGCTGGTTATGTCTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(92-236)

Helicase conserved C-terminal domain (Helicase_C)

(295-394)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

66.821

100

0.668
  comFA/cflA Streptococcus pneumoniae Rx1

66.357

100

0.664
  comFA/cflA Streptococcus pneumoniae D39

66.357

100

0.664
  comFA/cflA Streptococcus pneumoniae R6

66.357

100

0.664
  comFA/cflA Streptococcus pneumoniae TIGR4

66.357

100

0.664
  comFA/cflA Streptococcus mitis SK321

65.661

100

0.657
  comFA Lactococcus lactis subsp. cremoris KW2

53.904

92.111

0.497
  comFA Latilactobacillus sakei subsp. sakei 23K

37.875

100

0.381

Multiple sequence alignment