Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD   Type   Regulator
Locus tag   Locus_0 Genome accession   AF498313
Coordinates   133..1452 (+) Length   439 a.a.
NCBI ID   AAM18090.1    Uniprot ID   -
Organism   Streptococcus infantis strain Atu-4     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1..6452
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Locus_0 comD 133..1452 (+) 1320 AAM18090.1 histidine kinase ComD Regulator
  Locus_1 comE 1453..2205 (+) 753 AAM18091.1 response regulator ComE Regulator

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 51546.86 Da        Isoelectric Point: 6.4221

>NTDB_id=20003 Locus_0 AAM18090.1 133..1452(+) (comD) [Streptococcus infantis strain Atu-4]
MDLLKILIVILHILILTNSYELICKATKKERYLFISWVFILQSIVEILFYLTSLHGLGMEKISFTCIIFAYLIGFKKYNK
FKAIFISLLLSLLYQSTHTFIAVIISSLTGDSFLIKYEDLFFVVVLMLTYFVIKKIIFYFHLEINYFDKDYLYPFFKKVI
FAFFALHILLFISDMVNIHEHFYSFSSILATIVFICLLLIFFAMNAKKVQIEKEIALKQKKFEQEHLQTYTDEIVGLYNE
IRGFRHDYAGMLVSMQMAIDSKDLQEIDRIYNEVLVKANQKLRSDKYTYFDLNNIEDTALRSLIAQSIVYARNKDVEFTL
EVKDIITKLSIDLLDLVRIMSVLLNNAVEGAAESYSKQMEVAVIKMDLEIVIVIQNSCKYTMMPSEDLFELGFSTKGRNR
GIGLNNVKEILDQYENIILETEMEDSKFRQIIRFKREFE

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=20003 Locus_0 AAM18090.1 133..1452(+) (comD) [Streptococcus infantis strain Atu-4]
ATGGATTTATTGAAAATACTCATAGTTATTCTTCATATTCTTATTCTAACAAATAGCTATGAACTCATTTGTAAGGCAAC
AAAAAAAGAAAGATATCTGTTTATTTCTTGGGTATTTATATTACAGTCTATTGTTGAAATTTTATTCTATTTAACTTCTT
TACATGGATTAGGAATGGAAAAAATTTCATTTACCTGTATTATCTTTGCTTATTTAATAGGATTTAAAAAATATAATAAG
TTCAAAGCTATTTTTATTAGTTTATTATTGTCTTTATTATATCAAAGTACTCATACATTTATAGCAGTAATCATATCCTC
TTTAACAGGTGATTCTTTCTTAATAAAATATGAAGATTTATTTTTTGTAGTGGTTTTAATGCTGACCTATTTTGTAATCA
AAAAAATTATTTTTTATTTCCACTTGGAAATCAATTATTTTGATAAAGATTACCTCTATCCATTTTTTAAAAAGGTCATT
TTTGCTTTCTTTGCTTTACATATTCTATTATTTATTTCAGACATGGTGAATATTCATGAACACTTTTATAGTTTTAGTAG
TATTTTAGCAACAATTGTCTTTATTTGTTTACTACTAATCTTCTTTGCAATGAATGCCAAGAAGGTTCAAATTGAAAAAG
AAATAGCCCTAAAACAGAAAAAATTTGAACAAGAACATTTACAGACCTATACAGATGAAATTGTTGGTTTGTATAATGAA
ATCCGTGGTTTCCGTCATGATTATGCAGGTATGCTTGTCAGTATGCAAATGGCTATTGACAGTAAAGATTTACAGGAAAT
TGACAGAATTTACAATGAAGTCTTAGTAAAAGCTAATCAAAAATTACGTTCAGATAAGTATACATACTTTGATTTAAACA
ATATAGAAGATACAGCTTTACGAAGTTTAATTGCACAATCCATTGTATATGCAAGAAATAAGGACGTAGAGTTTACACTA
GAAGTAAAGGATATCATCACAAAGTTGTCAATTGATTTACTTGATCTTGTGCGTATTATGAGCGTTTTATTGAACAATGC
TGTCGAAGGTGCTGCAGAAAGTTACTCGAAACAAATGGAGGTTGCAGTGATTAAGATGGATTTAGAAATAGTTATCGTGA
TTCAAAATTCGTGTAAATATACTATGATGCCTTCAGAAGACTTGTTTGAACTAGGTTTTTCTACTAAAGGTAGAAATAGA
GGAATAGGCCTTAATAATGTCAAAGAGATTTTGGATCAGTATGAAAATATCATTTTAGAGACAGAGATGGAAGATAGTAA
GTTTAGACAGATTATTAGATTTAAGAGAGAGTTTGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(333-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD Streptococcus mitis NCTC 12261

71.655

100

0.72
  comD/comD2 Streptococcus pneumoniae TIGR4

70.975

100

0.713
  comD/comD1 Streptococcus pneumoniae Rx1

69.615

100

0.699
  comD/comD1 Streptococcus pneumoniae D39

69.615

100

0.699
  comD/comD1 Streptococcus pneumoniae R6

69.615

100

0.699
  comD Streptococcus mitis SK321

69.388

100

0.697
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

49.596

84.51

0.419
  comD/comD2 Streptococcus gordonii strain NCTC7865

48.541

85.877

0.417

Multiple sequence alignment