Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CE141_RS02255 Genome accession   NZ_CP022164
Coordinates   464490..465122 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain M160133     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 459490..470122
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CE141_RS02230 (CE141_02225) yhfG 459611..459778 (+) 168 WP_000736858.1 YhfG family protein -
  CE141_RS02235 (CE141_02230) fic 459768..460370 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  CE141_RS02240 (CE141_02235) pabA 460402..460965 (+) 564 WP_000601837.1 aminodeoxychorismate synthase component 2 -
  CE141_RS02245 (CE141_02240) argD 461051..462271 (+) 1221 WP_032172363.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CE141_RS02250 (CE141_02245) yhfK 462349..464439 (-) 2091 WP_001571992.1 YccS/YhfK family putative transporter -
  CE141_RS02255 (CE141_02250) crp 464490..465122 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CE141_RS02265 (CE141_02260) yhfA 465424..465828 (+) 405 WP_001148908.1 OsmC family protein -
  CE141_RS02270 (CE141_02265) prkB 465883..466752 (-) 870 WP_001274680.1 phosphoribulokinase -
  CE141_RS02275 (CE141_02270) yheU 466806..467024 (-) 219 WP_000907085.1 YheU family protein -
  CE141_RS02280 (CE141_02275) yheT 467018..468040 (-) 1023 WP_022646191.1 hydrolase -
  CE141_RS02285 (CE141_02280) yheS 468040..469953 (-) 1914 WP_000634789.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=199615 CE141_RS02255 WP_000242755.1 464490..465122(-) (crp) [Escherichia coli strain M160133]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=199615 CE141_RS02255 WP_000242755.1 464490..465122(-) (crp) [Escherichia coli strain M160133]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAAGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467