Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   BJG89_RS05370 Genome accession   NZ_CP017466
Coordinates   1167378..1168007 (+) Length   209 a.a.
NCBI ID   WP_096808931.1    Uniprot ID   A0A291JJY1
Organism   Staphylococcus nepalensis strain JS11     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1162378..1173007
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BJG89_RS05340 (BJG89_05250) - 1162397..1163122 (+) 726 WP_096808920.1 type 1 glutamine amidotransferase -
  BJG89_RS05345 (BJG89_05255) - 1163223..1164209 (-) 987 WP_096808922.1 FUSC family protein -
  BJG89_RS05350 (BJG89_05260) map 1164387..1165139 (+) 753 WP_096808923.1 type I methionyl aminopeptidase -
  BJG89_RS05355 (BJG89_05265) - 1165244..1165630 (+) 387 WP_096808925.1 hypothetical protein -
  BJG89_RS05360 (BJG89_05270) liaF 1165647..1166348 (+) 702 WP_096808927.1 cell wall-active antibiotics response protein LiaF -
  BJG89_RS05365 (BJG89_05275) vraS 1166345..1167388 (+) 1044 WP_096808929.1 sensor histidine kinase Regulator
  BJG89_RS05370 (BJG89_05280) vraR 1167378..1168007 (+) 630 WP_096808931.1 response regulator transcription factor Regulator
  BJG89_RS05375 (BJG89_05285) - 1168080..1169171 (-) 1092 WP_096808934.1 YihY/virulence factor BrkB family protein -
  BJG89_RS05380 (BJG89_05290) - 1169460..1169744 (-) 285 WP_096808936.1 YtxH domain-containing protein -
  BJG89_RS05385 (BJG89_05295) - 1169751..1170215 (-) 465 WP_096808938.1 low molecular weight protein-tyrosine-phosphatase -
  BJG89_RS05390 (BJG89_05300) - 1170348..1170551 (+) 204 WP_096808941.1 DUF1128 family protein -
  BJG89_RS05395 (BJG89_05305) - 1170566..1171807 (+) 1242 WP_096808943.1 aminopeptidase -
  BJG89_RS05400 (BJG89_05310) - 1171983..1172504 (+) 522 WP_096808945.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23752.27 Da        Isoelectric Point: 5.0024

>NTDB_id=198552 BJG89_RS05370 WP_096808931.1 1167378..1168007(+) (vraR) [Staphylococcus nepalensis strain JS11]
MPIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGQSGKDAIKKAHELHPDLILMDLLMDDMDGVEATEQIKKDLPHIKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAIRKTYHNESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNVLSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=198552 BJG89_RS05370 WP_096808931.1 1167378..1168007(+) (vraR) [Staphylococcus nepalensis strain JS11]
ATGCCGATTAAAGTATTGTTTGTTGATGACCATGAAATGGTTCGAATCGGAATTTCTAGTTATTTATCTACACAATCAGA
CATAGAAGTAGTTGGAGAAGGGCAATCAGGAAAAGATGCAATAAAAAAAGCACATGAACTACATCCTGATTTAATTTTAA
TGGATTTATTAATGGATGATATGGATGGCGTAGAAGCAACAGAACAAATAAAAAAAGATTTGCCGCATATTAAAGTGGTT
ATGTTAACAAGTTATATTGAAGATAATGAAGTGTACCGCGCTTTAGATTCAGGTGTCGATAGTTATATTTTAAAAACGAC
AAGTGCGAGTGACATTGCTGAAGCTATTCGTAAAACATATCACAATGAGTCTGTATTTGAAGCTGAAGTATTAGTTAAAA
TGAGAAATCGCATGAAACAACGTGCTGAATTGTATGAAATGTTAACTGAGCGAGAAATGGAAATCTTATTATTAATTGCA
AAAGGTTATTCAAACCAAGAAATAGCTAGCGCTTCCCACATTACGATTAAGACGGTTAAAACACATGTGAGTAATGTATT
AAGCAAATTAGAGGTACAAGATAGAACACAAGCTGTTATTTATGCATTCCAACATAATTTAATACAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A291JJY1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

89.952

100

0.9
  degU Bacillus subtilis subsp. subtilis str. 168

33.929

100

0.364

Multiple sequence alignment