Detailed information NTG0198551

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: BJG89_RS05365
• Genome accession: NZ_CP017466
• Coordinates: 1166345..1167388 (+)
• Length: 347 a.a.
• NCBI ID: WP_096808929.1
• Uniprot ID: A0A291JJJ1
• Organism: Staphylococcus nepalensis strain JS11
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1161345..1172388

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BJG89_RS05340 (BJG89_05250)	-	1162397..1163122 (+)	726	WP_096808920.1	type 1 glutamine amidotransferase	-
BJG89_RS05345 (BJG89_05255)	-	1163223..1164209 (-)	987	WP_096808922.1	FUSC family protein	-
BJG89_RS05350 (BJG89_05260)	map	1164387..1165139 (+)	753	WP_096808923.1	type I methionyl aminopeptidase	-
BJG89_RS05355 (BJG89_05265)	-	1165244..1165630 (+)	387	WP_096808925.1	hypothetical protein	-
BJG89_RS05360 (BJG89_05270)	liaF	1165647..1166348 (+)	702	WP_096808927.1	cell wall-active antibiotics response protein LiaF	-
BJG89_RS05365 (BJG89_05275)	vraS	1166345..1167388 (+)	1044	WP_096808929.1	sensor histidine kinase	Regulator
BJG89_RS05370 (BJG89_05280)	vraR	1167378..1168007 (+)	630	WP_096808931.1	response regulator transcription factor	Regulator
BJG89_RS05375 (BJG89_05285)	-	1168080..1169171 (-)	1092	WP_096808934.1	YihY/virulence factor BrkB family protein	-
BJG89_RS05380 (BJG89_05290)	-	1169460..1169744 (-)	285	WP_096808936.1	YtxH domain-containing protein	-
BJG89_RS05385 (BJG89_05295)	-	1169751..1170215 (-)	465	WP_096808938.1	low molecular weight protein-tyrosine-phosphatase	-
BJG89_RS05390 (BJG89_05300)	-	1170348..1170551 (+)	204	WP_096808941.1	DUF1128 family protein	-
BJG89_RS05395 (BJG89_05305)	-	1170566..1171807 (+)	1242	WP_096808943.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39940.35 Da
• Isoelectric Point: 6.0563

>NTDB_id=198551 BJG89_RS05365 WP_096808929.1 1166345..1167388(+) (vraS) [Staphylococcus nepalensis strain JS11]
MNHYIRAIGSMLILVYSTFFAMFFIDKVFVNIIYFQGMIYTQIFGIPVLLFINLLVILLCIIVGSVLAYKINQQNHWLQD
QIERSIEGQTVGINDQNIELYNETIELYQALVPLNQEVHKLRMKTQNLTNESYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETELQAPLDQQIPVLEKMVQDSQLEMRALLLHLRPIGLKDKSLGQGIKDLVVDLQKKVPMKVVHDI
EDFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNREEYLLLRIQDDGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSNAD

Nucleotide

• Length: 1044 bp

>NTDB_id=198551 BJG89_RS05365 WP_096808929.1 1166345..1167388(+) (vraS) [Staphylococcus nepalensis strain JS11]
ATGAATCACTACATAAGAGCAATAGGGTCAATGTTGATATTAGTATATAGTACTTTTTTCGCCATGTTTTTTATAGACAA
AGTATTTGTTAATATCATATATTTCCAAGGCATGATTTACACACAAATATTTGGCATACCAGTTTTATTATTTATAAACT
TGTTAGTTATATTACTTTGTATCATCGTTGGATCTGTATTAGCATATAAAATTAATCAACAGAATCATTGGTTACAAGAT
CAAATTGAGCGCTCCATAGAAGGCCAAACAGTAGGTATCAATGACCAAAATATAGAGTTGTACAATGAAACCATTGAATT
ATATCAAGCACTGGTACCACTTAATCAAGAAGTTCACAAGTTGCGTATGAAAACGCAAAATTTAACAAACGAATCATATA
ATATGAATGACGTGAAAGTTAAAAAAATAATAGAAGACGAACGACAAAGGTTGGCTCGTGAACTACATGATTCTGTAAGC
CAACAATTATTTGCAGCAAGCATGATGCTTTCAGCAATTAAAGAAACTGAATTACAAGCGCCTTTAGATCAACAAATTCC
AGTACTCGAAAAAATGGTTCAAGATTCACAATTAGAAATGCGCGCATTACTATTACATTTAAGACCAATTGGTTTGAAGG
ATAAATCACTAGGCCAAGGTATCAAAGATTTAGTTGTTGACTTGCAGAAAAAAGTACCCATGAAAGTCGTACACGATATT
GAAGACTTCAAAGTACCCAAAGGTATTGAAGATCACTTATTTCGGATTACCCAAGAGGCAATTTCAAATACATTAAGACA
TTCGAAAGGTACTAAAGTTACAATTGAATTATTTAATAGAGAAGAATATTTATTATTACGTATACAAGATGACGGTAAAG
GCTTTAACGTAGATGATAAGGTAGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGCGCCCTTGAAATTGGTGCAACT
TTCCATATCGTATCTCTGCCAGATTCAGGCACGCGAATTGAAGTCAAGGCCCCATTAAATAAGGAGGATTCAAATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A291JJJ1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	86.744	100	0.867