Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CDH89_RS03805 Genome accession   NZ_CP021844
Coordinates   748206..748865 (-) Length   219 a.a.
NCBI ID   WP_021574775.1    Uniprot ID   -
Organism   Escherichia coli strain EC1515     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 743206..753865
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CDH89_RS03780 (CDH89_03780) - 743948..744895 (+) 948 WP_001305988.1 iron-siderophore ABC transporter substrate-binding protein -
  CDH89_RS03785 (CDH89_03785) - 744892..745779 (+) 888 WP_000614954.1 MurR/RpiR family transcriptional regulator -
  CDH89_RS03790 (CDH89_03790) ygiN 745824..746138 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  CDH89_RS03795 (CDH89_03795) mdaB 746169..746750 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  CDH89_RS03800 (CDH89_03800) qseC 746860..748209 (-) 1350 WP_088172214.1 quorum sensing histidine kinase QseC -
  CDH89_RS03805 (CDH89_03805) ciaR 748206..748865 (-) 660 WP_021574775.1 quorum sensing response regulator transcription factor QseB Regulator
  CDH89_RS03810 (CDH89_03810) ygiW 749017..749409 (+) 393 WP_039060162.1 OB fold stress tolerance protein YgiW -
  CDH89_RS03815 (CDH89_03815) ygiV 749462..749944 (+) 483 WP_088172213.1 GyrI-like domain-containing protein -
  CDH89_RS03820 (CDH89_03820) ygiS 750053..751660 (+) 1608 WP_088172212.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24704.67 Da        Isoelectric Point: 6.3527

>NTDB_id=196659 CDH89_RS03805 WP_021574775.1 748206..748865(-) (ciaR) [Escherichia coli strain EC1515]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGCQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLILKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=196659 CDH89_RS03805 WP_021574775.1 748206..748865(-) (ciaR) [Escherichia coli strain EC1515]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTTGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAATACTGAAACCAAAAGAATTTGCTCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGCAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365

Multiple sequence alignment