Detailed information NTG0196043

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: BGV84_RS23480
• Genome accession: NZ_CP017149
• Coordinates: 5094484..5095821 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain ATCC 15692
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5089484..5100821

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BGV84_RS23455 (BGV84_23455)	pgeF	5089627..5090355 (-)	729	WP_003112833.1	peptidoglycan editing factor PgeF	-
BGV84_RS23460 (BGV84_23460)	rluD	5090352..5091314 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
BGV84_RS23465 (BGV84_23465)	-	5091460..5092485 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
BGV84_RS23470 (BGV84_23470)	-	5092642..5092887 (+)	246	WP_003102591.1	PP0621 family protein	-
BGV84_RS23475 (BGV84_23475)	pilS	5092877..5094469 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
BGV84_RS23480 (BGV84_23480)	pilR	5094484..5095821 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
BGV84_RS23485 (BGV84_23485)	thiO	5095867..5096961 (-)	1095	WP_010895678.1	glycine oxidase ThiO	-
BGV84_RS23490 (BGV84_23490)	-	5097096..5097605 (+)	510	WP_003112829.1	GspH/FimT family pseudopilin	-
BGV84_RS23495 (BGV84_23495)	-	5097711..5098217 (+)	507	WP_003102598.1	GspH/FimT family pseudopilin	-
BGV84_RS23500 (BGV84_23500)	pilV	5098208..5098765 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
BGV84_RS23505 (BGV84_23505)	pilW	5098762..5099586 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
BGV84_RS23510 (BGV84_23510)	pilX	5099583..5100170 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=196043 BGV84_RS23480 WP_003094694.1 5094484..5095821(+) (pilR) [Pseudomonas aeruginosa strain ATCC 15692]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=196043 BGV84_RS23480 WP_003094694.1 5094484..5095821(+) (pilR) [Pseudomonas aeruginosa strain ATCC 15692]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384