Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CDH85_RS04465 Genome accession   NZ_CP021769
Coordinates   802655..803329 (+) Length   224 a.a.
NCBI ID   WP_001238600.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain B509     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 797655..808329
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CDH85_RS04450 (CDH85_04430) - 798653..800380 (+) 1728 WP_000429358.1 ABC transporter permease/substrate binding protein -
  CDH85_RS04455 (CDH85_04435) - 800626..801981 (+) 1356 WP_000712231.1 YjiH family protein -
  CDH85_RS04460 (CDH85_04440) rpmH 802165..802299 (+) 135 WP_112435766.1 50S ribosomal protein L34 -
  CDH85_RS04465 (CDH85_04445) ciaR 802655..803329 (+) 675 WP_001238600.1 two-component system response regulator DltR Regulator
  CDH85_RS04470 (CDH85_04450) dltS 803329..804516 (+) 1188 WP_000490535.1 two-component system sensor histidine kinase DltS -
  CDH85_RS04475 (CDH85_04455) - 804527..804649 (+) 123 WP_000806141.1 teichoic acid D-Ala incorporation-associated protein DltX -
  CDH85_RS04480 (CDH85_04460) dltA 804662..806197 (+) 1536 WP_000581010.1 D-alanine--poly(phosphoribitol) ligase subunit DltA -
  CDH85_RS04485 (CDH85_04465) dltB 806194..807459 (+) 1266 WP_112435768.1 D-alanyl-lipoteichoic acid biosynthesis protein DltB -
  CDH85_RS04490 (CDH85_04470) dltC 807474..807713 (+) 240 WP_000351975.1 D-alanine--poly(phosphoribitol) ligase subunit DltC -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25521.52 Da        Isoelectric Point: 5.2130

>NTDB_id=195799 CDH85_RS04465 WP_001238600.1 802655..803329(+) (ciaR) [Streptococcus agalactiae strain B509]
MRLLVVEDEKSIAEAIQALLADKGYSVDLVFDGDDGLEYILTGLYDLVLLDIMLPKRSGLSILKRVREAGLETPIIFLTA
KSQTYDKVNGLDLGADDYITKPFEADELLARIRLRTRQSSLIRANQLRLGNIRLNTDSHELESKESSVKLSNKEFLLMEV
FMRNAKQIIPKNQLISKVWGPSDNSEYNQLEVFISFLRKKLRFLKADIEIITTKGFGYSLEEMT

Nucleotide


Download         Length: 675 bp        

>NTDB_id=195799 CDH85_RS04465 WP_001238600.1 802655..803329(+) (ciaR) [Streptococcus agalactiae strain B509]
ATGAGACTTCTTGTAGTTGAGGATGAAAAAAGTATAGCAGAGGCTATTCAGGCTTTATTGGCAGATAAAGGTTATTCTGT
TGATTTAGTATTTGATGGAGATGATGGGTTAGAATACATTTTGACAGGTCTCTATGATTTAGTCTTGTTGGATATTATGT
TACCCAAACGCTCAGGATTATCTATTTTAAAAAGAGTGAGGGAAGCTGGTTTAGAAACCCCAATAATCTTTTTAACTGCA
AAATCACAGACTTATGATAAAGTTAATGGTTTAGATTTAGGGGCAGATGATTATATCACAAAACCCTTTGAAGCAGATGA
ATTGCTAGCTAGAATTAGGTTGAGAACCAGACAATCTTCTCTGATCAGAGCAAATCAATTGCGGCTTGGAAATATAAGGC
TTAACACAGATTCACATGAGCTAGAATCTAAAGAAAGTAGTGTAAAATTATCCAATAAAGAATTTCTCTTGATGGAAGTT
TTTATGCGAAATGCAAAGCAGATTATTCCTAAAAACCAGTTGATTTCTAAGGTTTGGGGACCTTCAGACAATTCAGAATA
TAACCAGTTAGAAGTATTTATTTCTTTTTTGCGAAAAAAATTGCGCTTTTTAAAAGCAGACATTGAAATAATAACCACTA
AGGGCTTTGGATATTCCTTGGAGGAGATGACATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

37.838

99.107

0.375
  ciaR Streptococcus pneumoniae Rx1

37.22

99.554

0.371
  ciaR Streptococcus pneumoniae D39

37.22

99.554

0.371
  ciaR Streptococcus pneumoniae R6

37.22

99.554

0.371
  ciaR Streptococcus pneumoniae TIGR4

37.22

99.554

0.371