Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   A7J08_RS02435 Genome accession   NZ_CP017088
Coordinates   470924..472216 (+) Length   430 a.a.
NCBI ID   WP_053867077.1    Uniprot ID   A0A3S6JJD4
Organism   Streptococcus suis strain SRD478     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 465924..477216
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J08_RS02410 (A7J08_02320) - 466729..467370 (+) 642 WP_079394183.1 response regulator transcription factor -
  A7J08_RS02415 (A7J08_02325) - 467420..468820 (+) 1401 WP_053867074.1 Cof-type HAD-IIB family hydrolase -
  A7J08_RS02420 (A7J08_02330) - 468822..469193 (+) 372 WP_024394815.1 S1 RNA-binding domain-containing protein -
  A7J08_RS02425 (A7J08_02335) cysK 469220..470146 (-) 927 WP_053867075.1 cysteine synthase A -
  A7J08_RS02430 (A7J08_02340) - 470235..470867 (-) 633 WP_053867076.1 YigZ family protein -
  A7J08_RS02435 (A7J08_02345) comFA/cflA 470924..472216 (+) 1293 WP_053867077.1 DEAD/DEAH box helicase Machinery gene
  A7J08_RS02440 (A7J08_02350) - 472209..472874 (+) 666 WP_053867078.1 ComF family protein -
  A7J08_RS02445 (A7J08_02355) raiA 472951..473493 (+) 543 WP_014637536.1 ribosome-associated translation inhibitor RaiA -
  A7J08_RS02450 (A7J08_02360) - 473634..474764 (+) 1131 WP_053867079.1 ISAs1 family transposase -
  A7J08_RS02455 (A7J08_02365) - 474766..475086 (+) 321 WP_235443470.1 hypothetical protein -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48885.39 Da        Isoelectric Point: 9.1612

>NTDB_id=195391 A7J08_RS02435 WP_053867077.1 470924..472216(+) (comFA/cflA) [Streptococcus suis strain SRD478]
MKELENYYGRLFTKYQLTAKEREIAEKVPSITKKNNCFRCGTTFEEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKDF
PITKCLKWKGQLTDWQQRISDGLVANVENNRATLVHAVTGAGKTEMIYHTVASVVDKGGAVCLASPRIDVCIELYKRLQN
DFSIPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYRAADNAVKEAGVQVFLTATSTDEL
DKKVRTGKLSRLSLPRRFHGNPLVVPQKVWFSKFDDTLKKNRLVPKLKKAIEEQRKSGFPLLIFVPEISKGQEFTKIMKK
TFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLYTASSLVQIAGRVGRSTERPTG
LLQFYHEGSTGAIEKAIAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=195391 A7J08_RS02435 WP_053867077.1 470924..472216(+) (comFA/cflA) [Streptococcus suis strain SRD478]
ATGAAAGAATTAGAAAATTATTATGGAAGATTATTTACCAAATACCAATTGACAGCAAAAGAAAGAGAAATAGCAGAAAA
AGTGCCAAGTATTACAAAAAAGAATAACTGCTTTCGCTGTGGAACAACTTTTGAAGAAGAAAACAAATTGCCAAACGATG
CTTATTATTGTCGAGCCTGCTTGCTTCTAGGCAGAGTACGGTCAGACGAAAAACTCTATCATTTTCCTCAGAAAGATTTT
CCAATCACTAAGTGTTTAAAGTGGAAAGGTCAACTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGT
GGAAAATAATCGTGCAACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATTTACCACACCGTTGCCTCAG
TGGTTGATAAAGGCGGAGCGGTTTGCCTAGCCAGTCCTCGAATCGATGTTTGTATCGAACTCTATAAACGTCTGCAAAAT
GACTTTTCAATTCCAATTAGTTTACTACATGGAGAGTCTGAACCCTATTTCCGAACTCCATTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCAGATAATCCCA
TGCTCTATCGAGCAGCAGATAATGCAGTCAAGGAAGCCGGTGTTCAAGTTTTTCTGACAGCGACTTCAACAGATGAATTG
GATAAAAAAGTCAGAACAGGCAAATTAAGCCGTCTTAGTTTGCCAAGGCGCTTTCATGGCAACCCACTTGTTGTCCCGCA
AAAAGTCTGGTTTAGTAAATTCGATGATACCCTAAAGAAAAATAGACTAGTTCCAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAAAGTCGGGCTTCCCCTTACTCATTTTTGTCCCAGAAATCTCTAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ACATTCCCAGAAGAAACAATTGGCTTTGTATCCAGTCAAACAGAAAATCGCCTTGAAATAGTTGAAGGGTTTCGCAAGAG
AGAAATCACAGTCTTAATCTCGACTACTATTCTTGAACGTGGGGTGACCTTCCCATGTGTAGACGTCTTTGTTGTTCAAG
CCAATCATTACCTCTACACAGCGTCAAGTCTTGTTCAGATTGCAGGCCGGGTCGGAAGGAGTACAGAACGTCCGACTGGT
TTACTTCAGTTTTATCATGAGGGAAGTACAGGAGCCATTGAAAAGGCAATCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGTTATGTCTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(91-235)

Helicase conserved C-terminal domain (Helicase_C)

(289-394)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3S6JJD4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

66.821

100

0.67
  comFA/cflA Streptococcus pneumoniae Rx1

66.125

100

0.663
  comFA/cflA Streptococcus pneumoniae D39

66.125

100

0.663
  comFA/cflA Streptococcus pneumoniae R6

66.125

100

0.663
  comFA/cflA Streptococcus pneumoniae TIGR4

66.125

100

0.663
  comFA/cflA Streptococcus mitis SK321

65.661

100

0.658
  comFA Lactococcus lactis subsp. cremoris KW2

54.156

92.326

0.5
  comFA Latilactobacillus sakei subsp. sakei 23K

38.051

100

0.381
  comFA Bacillus subtilis subsp. subtilis str. 168

37.59

96.512

0.363

Multiple sequence alignment