Detailed information    

insolico Bioinformatically predicted

Overview

Name   comP   Type   Machinery gene
Locus tag   CCD88_RS11540 Genome accession   NZ_CP021724
Coordinates   2031869..2032318 (+) Length   149 a.a.
NCBI ID   WP_002214937.1    Uniprot ID   Q9JXJ2
Organism   Neisseria meningitidis strain 12-330     
Function   DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2026869..2037318
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CCD88_RS11535 (CCD88_11730) comE 2031317..2031781 (+) 465 WP_010981060.1 ComEA family DNA-binding protein Machinery gene
  CCD88_RS11540 (CCD88_11735) comP 2031869..2032318 (+) 450 WP_002214937.1 type IV pilin protein Machinery gene
  CCD88_RS13270 (CCD88_11740) - 2032408..2032748 (-) 341 Protein_1969 5'-nucleotidase -
  CCD88_RS11550 (CCD88_11745) - 2032860..2033072 (-) 213 WP_002224145.1 SWIM zinc finger domain-containing protein -
  CCD88_RS11555 (CCD88_11755) - 2033304..2033777 (+) 474 Protein_1971 IS5/IS1182 family transposase -
  CCD88_RS11565 (CCD88_11765) - 2034131..2035591 (-) 1461 WP_002230014.1 VWA domain-containing protein -
  CCD88_RS11570 (CCD88_11770) - 2035582..2037189 (-) 1608 WP_002230016.1 AAA family ATPase -

Sequence

Protein


Download         Length: 149 a.a.        Molecular weight: 16834.81 Da        Isoelectric Point: 9.7951

>NTDB_id=195367 CCD88_RS11540 WP_002214937.1 2031869..2032318(+) (comP) [Neisseria meningitidis strain 12-330]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide


Download         Length: 450 bp        

>NTDB_id=195367 CCD88_RS11540 WP_002214937.1 2031869..2032318(+) (comP) [Neisseria meningitidis strain 12-330]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCCTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterProScan.

Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS)

(28-107)

Prokaryotic N-terminal methylation motif (N_methyl)

(1-27)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9JXJ2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Neisseria gonorrhoeae MS11

100

100

1
  comP Neisseria meningitidis 8013

99.329

100

0.993
  comP Neisseria subflava NJ9703

49.66

98.658

0.49

Multiple sequence alignment