Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE1   Type   Regulator
Locus tag   BGL51_RS05005 Genome accession   NZ_CP017064
Coordinates   927410..928090 (+) Length   226 a.a.
NCBI ID   WP_095559359.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ST3     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 922410..933090
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BGL51_RS04965 (BGL51_04920) - 922458..922640 (+) 183 WP_006531883.1 Blp family class II bacteriocin -
  BGL51_RS04975 (BGL51_04925) - 923257..923487 (+) 231 WP_043878356.1 bacteriocin -
  BGL51_RS04980 (BGL51_04930) - 923576..923887 (+) 312 WP_003066586.1 hypothetical protein -
  BGL51_RS04985 (BGL51_04935) - 924101..924193 (+) 93 Protein_908 Blp family class II bacteriocin -
  BGL51_RS04990 (BGL51_04940) - 924251..924655 (+) 405 WP_015695682.1 hypothetical protein -
  BGL51_RS04995 (BGL51_04945) - 924836..925882 (+) 1047 WP_095559358.1 thioredoxin fold domain-containing protein -
  BGL51_RS05000 (BGL51_04950) - 926414..927178 (+) 765 WP_232086163.1 DUF6261 family protein -
  BGL51_RS05005 (BGL51_04955) comE/comE1 927410..928090 (+) 681 WP_095559359.1 LytR/AlgR family response regulator transcription factor Regulator
  BGL51_RS05010 (BGL51_04960) - 928103..929422 (+) 1320 WP_095559360.1 sensor histidine kinase -
  BGL51_RS05015 (BGL51_04965) - 929443..929592 (-) 150 WP_006531893.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  BGL51_RS05025 (BGL51_04975) - 930119..930703 (+) 585 WP_232086162.1 hypothetical protein -
  BGL51_RS05030 (BGL51_04980) csm6 930718..931809 (+) 1092 WP_095559361.1 type III-A CRISPR-associated CARF protein Csm6 -
  BGL51_RS05035 (BGL51_04985) pyrF 932010..932705 (+) 696 WP_011681116.1 orotidine-5'-phosphate decarboxylase -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 26244.95 Da        Isoelectric Point: 5.6150

>NTDB_id=194976 BGL51_RS05005 WP_095559359.1 927410..928090(+) (comE/comE1) [Streptococcus thermophilus strain ST3]
MERAINLVMESNNWHYRYLEISSNPDEIIAVAGNGEHQIFFLDLEIKGEEQQGIDVAKAIREKNSTAIIVFVTTHSEFML
LTYQSLVGAIDFIDKGLNEEAFNERLFVCLKEAVKRQEGNFGEHSYLFHTPQAKVRVAYDDILFFETSPAPHRIILHTKN
ERTEFYATIAEVAKSDERLFRCHRSFVVNVDNIARFDMRYKLIYFEMGETCPVARAKVKLLQEKIE

Nucleotide


Download         Length: 681 bp        

>NTDB_id=194976 BGL51_RS05005 WP_095559359.1 927410..928090(+) (comE/comE1) [Streptococcus thermophilus strain ST3]
ATGGAGCGTGCTATTAATCTTGTGATGGAATCAAATAACTGGCATTATCGGTATTTGGAGATTTCATCTAATCCTGATGA
AATCATCGCAGTAGCAGGTAATGGTGAACATCAAATTTTCTTTCTTGATTTAGAAATTAAAGGTGAAGAGCAGCAAGGGA
TTGATGTTGCTAAAGCTATTCGTGAAAAAAATAGCACAGCTATTATTGTTTTTGTGACGACACATTCTGAATTCATGCTC
TTAACCTATCAATCTTTAGTAGGTGCTATTGACTTTATTGACAAAGGATTAAACGAAGAAGCGTTTAATGAACGCTTATT
CGTTTGTCTTAAAGAAGCTGTCAAACGCCAAGAGGGAAACTTTGGTGAACATTCCTACTTGTTTCATACCCCACAAGCCA
AAGTGCGGGTAGCTTATGATGATATTTTATTTTTTGAAACGTCACCAGCACCTCATCGTATTATTTTGCACACTAAGAAC
GAACGTACAGAATTTTATGCGACCATAGCAGAAGTGGCAAAATCAGATGAACGTCTTTTTAGATGTCATCGTTCTTTTGT
GGTTAACGTGGATAATATCGCTAGATTTGATATGAGGTATAAGCTCATTTATTTTGAGATGGGAGAAACCTGTCCTGTAG
CTAGGGCTAAGGTGAAATTATTACAGGAGAAAATTGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(16-105)

LytTr DNA-binding domain (LytTR)

(135-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE1 Streptococcus equinus JB1

65.315

98.23

0.642
  comE/blpR Streptococcus mutans UA159

44.934

100

0.451
  comE/comE2 Streptococcus equinus JB1

42.92

100

0.429

Multiple sequence alignment