Detailed information NTG0194038

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: BFM96_RS05145
• Genome accession: NZ_CP016953
• Coordinates: 1081609..1083762 (-)
• Length: 717 a.a.
• NCBI ID: WP_068991204.1
• Uniprot ID: A0A917A678
• Organism: Streptococcus himalayensis strain HTS2
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1076609..1088762

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BFM96_RS11340	-	1076917..1077303 (-)	387	WP_068991190.1	hypothetical protein	-
BFM96_RS05125	-	1077502..1077843 (+)	342	WP_068991194.1	LytTR family DNA-binding domain-containing protein	-
BFM96_RS05130	comE/blpR	1077845..1078582 (+)	738	WP_068991197.1	response regulator transcription factor	Regulator
BFM96_RS05135	-	1078596..1079933 (+)	1338	WP_068991199.1	GHKL domain-containing protein	-
BFM96_RS10840	-	1079984..1080142 (-)	159	WP_083201746.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
BFM96_RS05140	-	1080245..1081597 (-)	1353	WP_068991202.1	bacteriocin secretion accessory protein	-
BFM96_RS05145	comA/nlmT	1081609..1083762 (-)	2154	WP_068991204.1	peptide cleavage/export ABC transporter	Regulator
BFM96_RS05150	-	1084060..1084245 (+)	186	WP_068991207.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
BFM96_RS05155	-	1084267..1084473 (+)	207	WP_068991210.1	hypothetical protein	-
BFM96_RS05160	-	1084483..1084683 (+)	201	WP_068991213.1	hypothetical protein	-
BFM96_RS05165	-	1084792..1085400 (+)	609	WP_068991216.1	CPBP family intramembrane glutamic endopeptidase	-
BFM96_RS10845	-	1085498..1085644 (+)	147	Protein_978	helix-turn-helix domain-containing protein	-
BFM96_RS05170	-	1086116..1086289 (+)	174	WP_068991219.1	bacteriocin	-
BFM96_RS05175	-	1086383..1086667 (+)	285	WP_223245869.1	hypothetical protein	-
BFM96_RS11535	-	1086876..1086968 (-)	93	WP_373283966.1	helix-turn-helix domain-containing protein	-
BFM96_RS05180	-	1087317..1087547 (+)	231	WP_068991225.1	Blp family class II bacteriocin	-
BFM96_RS11080	-	1088345..1088521 (+)	177	WP_145939711.1	ComC/BlpC family peptide pheromone/bacteriocin	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80581.42 Da
• Isoelectric Point: 7.1816

>NTDB_id=194038 BFM96_RS05145 WP_068991204.1 1081609..1083762(-) (comA/nlmT) [Streptococcus himalayensis strain HTS2]
MTSYKRTFVPQIDARDCGVAALASIARFYGSNYSLAHLRELAKTNKEGTTALGIVKAANEMGFETRAIQADMTLFDMEDV
PYPFIVHVNKEGRLQHYYVVYQAKKDHLIIGDPDPTVKITKMTKERFATEWTGVAIFLAPEASYKPHKDKKNGLLSFLPL
IFKQSSLIFYIVLASLLVTLINISGSYYIQGILDEYIPNQMKSTLGIISIGLIVTYILQQMMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSLFLDVSILIIVGSVLLVQNTNLFLLSLISVPIYIA
IIFIFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEESRYQKIDSEFVDYLDKSFRLSKYSILQGTLKQGAQL
ILNTGILWFGARLAMDNSISIGQLITFNTLLSYFTHPLENIINLQTKLQSAKVANNRLNEVYLVESEFSDSQTLTDSQFL
SGDIQFEDLSYKYGFGRDTLSDINLTIKKGDKVSLVGISGSGKTTLAKMIVNFFEPYKGRITINNNDLKMVDKKVLRKHI
SYLPQQAYIFSGSVLENLTLGANQMIRQEDILRACEIAEIRHDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAS
VLILDEATSGLDVLTEKKVIDNLMTMTDKTIIFVAHRLSISERTNQVIVLDQGKIIETGSHQELMAKQGFYHHLFSK

Nucleotide

• Length: 2154 bp

>NTDB_id=194038 BFM96_RS05145 WP_068991204.1 1081609..1083762(-) (comA/nlmT) [Streptococcus himalayensis strain HTS2]
ATGACATCCTATAAACGAACATTTGTCCCACAGATTGATGCTAGGGACTGTGGTGTCGCTGCTTTAGCTTCTATCGCAAG
ATTCTACGGTTCGAACTATTCTCTAGCCCACTTGAGAGAGCTAGCAAAAACGAATAAGGAAGGGACGACTGCTCTTGGGA
TTGTAAAAGCCGCTAATGAGATGGGATTTGAAACAAGGGCTATTCAAGCAGATATGACTCTGTTTGATATGGAAGATGTA
CCTTATCCCTTTATCGTCCATGTCAATAAGGAGGGTAGACTCCAACACTACTATGTCGTCTATCAAGCAAAAAAAGACCA
TCTGATCATCGGTGACCCTGATCCGACAGTTAAGATCACGAAGATGACTAAAGAACGCTTTGCTACCGAATGGACAGGGG
TTGCCATTTTTCTAGCCCCTGAAGCAAGCTATAAGCCGCATAAAGATAAAAAGAACGGACTATTGAGTTTTCTTCCTTTA
ATTTTTAAACAGAGCTCTCTTATCTTCTATATTGTACTAGCAAGTCTCCTAGTCACTCTCATCAATATTAGCGGTTCTTA
CTATATTCAAGGAATTTTAGATGAATATATTCCTAATCAGATGAAGTCCACTTTAGGAATTATCTCTATTGGCTTGATTG
TCACCTATATTCTCCAGCAGATGATGAGTTTCTCTCGAGATTATCTTCTCACTGTATTGAGTCAGAGACTAAGTATTGAT
GTCATTCTATCTTATATCCGACACATCTTTGAATTACCCATGTCCTTTTTTGCCACACGGCGGACAGGGGAAGTGATCTC
CCGCTTTACAGATGCCAACTCCATCATTGACGCTTTAGCATCCACCATCCTATCCCTCTTTCTGGATGTCTCTATCCTCA
TCATCGTTGGCAGTGTCCTGCTGGTACAAAATACCAATCTTTTTTTACTATCACTGATTTCCGTCCCTATCTACATTGCC
ATTATTTTCATCTTTATGAAACCATTTGAAAAGATGAATCACGACGTTATGCAAAGCAATTCCATGGTCAGCTCAGCTAT
TATTGAAGATATTAACGGTATCGAAACCATCAAGTCATTAACTAGCGAAGAAAGTCGCTACCAGAAAATTGACAGCGAGT
TCGTTGACTATCTAGATAAGTCCTTTAGATTAAGTAAGTACTCTATCCTACAAGGAACTCTAAAACAAGGAGCTCAATTA
ATCCTTAATACGGGTATTCTCTGGTTTGGAGCTAGATTAGCAATGGATAACTCTATTTCTATTGGTCAACTAATTACCTT
CAATACACTGCTCAGCTATTTTACCCATCCTCTGGAAAATATCATCAACCTTCAAACAAAACTACAATCTGCAAAAGTAG
CTAATAATCGTCTCAACGAAGTTTATTTGGTTGAATCAGAATTTAGCGATAGTCAGACACTAACAGATAGCCAATTTCTT
TCTGGTGATATTCAGTTTGAAGACCTTTCCTACAAATATGGTTTTGGTCGTGACACCTTATCAGACATCAATCTGACAAT
CAAAAAAGGCGACAAGGTGAGTCTCGTAGGGATTAGTGGTTCAGGAAAGACGACTTTAGCTAAAATGATTGTCAACTTCT
TTGAACCCTACAAAGGACGCATCACCATTAACAATAACGACCTCAAAATGGTGGATAAAAAAGTATTGCGAAAACATATC
AGCTACCTCCCTCAACAAGCCTATATCTTTAGCGGTTCTGTTTTAGAGAATTTGACCTTGGGTGCTAATCAGATGATTCG
TCAAGAAGATATTTTAAGGGCTTGTGAAATTGCAGAGATCCGCCATGACATCGAACAGATGCCTATGGGCTATCAAACAG
AACTCTCTGACGGAGCAGGTCTGTCCGGTGGTCAAAAACAACGGATTGCCCTAGCCAGGGCTCTTCTCACCAAAGCTTCT
GTTCTCATACTCGATGAAGCGACAAGCGGTCTTGATGTCCTGACAGAAAAAAAGGTGATTGATAACCTGATGACGATGAC
TGATAAAACCATTATTTTTGTAGCTCATCGACTTAGCATTTCTGAGCGAACCAATCAGGTCATTGTCCTTGACCAAGGAA
AAATTATTGAGACTGGCTCTCATCAGGAACTAATGGCTAAGCAAGGCTTCTACCATCATTTATTTAGTAAGTAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (168-438)

• ABC transporter (ABC_tran) (500-649)

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.867	99.721	0.727
comA	Streptococcus mitis NCTC 12261	67.37	99.163	0.668
comA	Streptococcus mitis SK321	66.807	99.163	0.662
comA	Streptococcus pneumoniae Rx1	66.667	99.163	0.661
comA	Streptococcus pneumoniae D39	66.667	99.163	0.661
comA	Streptococcus pneumoniae R6	66.667	99.163	0.661
comA	Streptococcus pneumoniae TIGR4	66.385	99.163	0.658
comA	Streptococcus gordonii str. Challis substr. CH1	65.175	99.721	0.65