Detailed information NTG0193584

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: S101267_RS20705
• Genome accession: NZ_CP021505
• Coordinates: 3984596..3985792 (-)
• Length: 398 a.a.
• NCBI ID: WP_013354214.1
• Uniprot ID: A0A9P1NK46
• Organism: Bacillus amyloliquefaciens strain SRCM101267
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 3979596..3990792

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
S101267_RS20690 (S101267_04158)	-	3981198..3982616 (-)	1419	WP_014471292.1	sensor histidine kinase	-
S101267_RS20695 (S101267_04159)	-	3982613..3983296 (-)	684	WP_013354212.1	response regulator transcription factor	-
S101267_RS20700 (S101267_04160)	-	3983510..3984223 (+)	714	WP_065118534.1	PepSY domain-containing protein	-
S101267_RS20705 (S101267_04161)	htrA	3984596..3985792 (-)	1197	WP_013354214.1	S1C family serine protease	Regulator
S101267_RS20710 (S101267_04162)	vicX	3985879..3986673 (-)	795	WP_013354215.1	MBL fold metallo-hydrolase	Regulator
S101267_RS20715 (S101267_04163)	-	3986689..3987528 (-)	840	WP_013354216.1	two-component system regulatory protein YycI	-
S101267_RS20720 (S101267_04164)	yycH	3987515..3988873 (-)	1359	WP_013354217.1	two-component system activity regulator YycH	-
S101267_RS20725 (S101267_04165)	walK	3988863..3990698 (-)	1836	WP_013354218.1	cell wall metabolism sensor histidine kinase WalK	-

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 42734.68 Da
• Isoelectric Point: 7.4579

>NTDB_id=193584 S101267_RS20705 WP_013354214.1 3984596..3985792(-) (htrA) [Bacillus amyloliquefaciens strain SRCM101267]
MDYNRDDEQYAPEQPRRSKRGYFLSSLIGVIVGAALMGLLLPYWTGGDHGESSKSANQRIGSEQVKTVNVNINDAVTNMV
SRVSDSVVGVLNIQKTDIWGEGGEAGSGSGVIYKKNGNTSYIVTNHHVIEGATEIEISLKDDSRVPAELIGSDRLMDLAV
LKVKTDKIKSVAQFGNSDQVKVGEPVIAIGNPLGLEFAGSVTQGIISGTERAVPVDSNGDGQPDWNAEVLQTDAAINPGN
SGGALMDISGKVVGINSMKIAESAVEGIGLSIPSKLVIPVIQDLEKYGEVRRPFLGIEMKSLTDIASYHWSQTLKLPKGV
KTGAVIMGVDAFSPAGKAGLKKLDVITGFDGHKVNDIVDLRERLYRKKIGDRVKITFYRSGKKKTAEVKLTEADRLQK

Nucleotide

• Length: 1197 bp

>NTDB_id=193584 S101267_RS20705 WP_013354214.1 3984596..3985792(-) (htrA) [Bacillus amyloliquefaciens strain SRCM101267]
GTGGATTATAATCGCGATGATGAACAGTACGCCCCCGAGCAGCCCCGCCGCAGCAAGAGAGGATACTTCCTTTCAAGTCT
GATCGGTGTCATCGTCGGGGCCGCGCTCATGGGTTTACTGCTGCCGTACTGGACAGGCGGAGACCATGGAGAAAGCAGCA
AAAGCGCCAATCAGCGCATCGGCAGCGAACAGGTGAAAACAGTCAACGTAAATATCAATGATGCTGTCACGAATATGGTC
AGCCGTGTATCGGATTCGGTAGTCGGCGTTCTCAATATCCAAAAGACCGATATTTGGGGAGAGGGCGGCGAAGCGGGAAG
CGGGTCCGGCGTCATTTACAAAAAGAACGGAAACACTTCTTATATCGTAACCAATCACCATGTCATTGAAGGTGCGACTG
AAATTGAGATCAGCCTGAAAGATGACTCGCGCGTGCCTGCCGAGCTGATCGGGAGCGACCGTCTGATGGATCTTGCCGTG
TTGAAGGTGAAGACTGATAAAATCAAATCGGTCGCCCAATTCGGCAATTCTGATCAAGTGAAAGTTGGCGAGCCGGTCAT
TGCGATCGGAAACCCGCTCGGACTTGAATTTGCGGGATCGGTGACACAAGGGATCATTTCAGGAACGGAAAGGGCGGTTC
CCGTTGACTCAAACGGCGACGGACAGCCTGATTGGAATGCGGAAGTGCTGCAGACCGACGCCGCGATTAATCCCGGCAAC
AGCGGCGGCGCTTTGATGGATATATCGGGCAAGGTGGTCGGCATCAACTCAATGAAGATTGCTGAATCCGCCGTTGAAGG
AATCGGCCTGTCCATCCCGTCAAAGCTTGTCATTCCCGTTATTCAGGATTTAGAAAAATACGGAGAAGTCAGACGGCCTT
TCCTCGGTATTGAGATGAAATCTTTAACGGATATTGCGAGCTACCATTGGAGCCAGACGCTCAAACTTCCGAAGGGTGTT
AAAACCGGAGCGGTCATTATGGGTGTCGACGCGTTTTCACCGGCTGGAAAAGCAGGCTTGAAAAAGCTCGACGTGATCAC
CGGATTCGACGGACATAAGGTCAATGACATTGTCGATCTCCGTGAGCGTCTGTATCGCAAAAAGATCGGCGACCGTGTCA
AGATCACGTTCTACCGTTCAGGAAAGAAAAAAACAGCGGAAGTCAAACTGACAGAAGCGGATCGATTGCAGAAATAA

Domains

Predicted by InterProScan.

• Trypsin-like peptidase domain (Trypsin_2) (108-255)

• PDZ domain (PDZ_2) (293-390)

• Peptidase family M50 (Peptidase_M50) (320-394)

3D structure

• AlphaFold DB: A0A9P1NK46

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	43.687	99.497	0.435
htrA	Streptococcus gordonii str. Challis substr. CH1	41.602	97.236	0.405
htrA	Streptococcus mitis NCTC 12261	40.26	96.734	0.389