Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EC95NR1_RS23825 Genome accession   NZ_CP021339
Coordinates   4452920..4453510 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain 95NR1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4447920..4458510
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EC95NR1_RS23810 (EC95NR1_03095) uhpT 4448442..4449833 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  EC95NR1_RS23815 (EC95NR1_03096) uhpC 4450089..4451408 (-) 1320 WP_001341770.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  EC95NR1_RS23820 (EC95NR1_03097) uhpB 4451418..4452920 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  EC95NR1_RS23825 (EC95NR1_03098) letA 4452920..4453510 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  EC95NR1_RS23830 (EC95NR1_03099) ilvN 4453585..4453875 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  EC95NR1_RS23835 (EC95NR1_03100) ilvB 4453879..4455567 (-) 1689 WP_000168480.1 acetolactate synthase large subunit -
  EC95NR1_RS23840 ivbL 4455673..4455771 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  EC95NR1_RS23860 (EC95NR1_03102) tisB 4456336..4456425 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  EC95NR1_RS31435 ysdE 4456688..4456762 (-) 75 WP_211180519.1 protein YsdE -
  EC95NR1_RS23870 (EC95NR1_03103) emrD 4456844..4458028 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=192777 EC95NR1_RS23825 WP_000633668.1 4452920..4453510(-) (letA) [Escherichia coli strain 95NR1]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=192777 EC95NR1_RS23825 WP_000633668.1 4452920..4453510(-) (letA) [Escherichia coli strain 95NR1]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment