Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EC95NR1_RS21940 Genome accession   NZ_CP021339
Coordinates   4062212..4062844 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 95NR1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4057212..4067844
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EC95NR1_RS21910 (EC95NR1_02732) yheS 4057381..4059294 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  EC95NR1_RS21915 (EC95NR1_02733) yheT 4059294..4060316 (+) 1023 WP_000057362.1 hydrolase -
  EC95NR1_RS21920 (EC95NR1_02734) yheU 4060310..4060528 (+) 219 WP_000907085.1 YheU family protein -
  EC95NR1_RS21925 (EC95NR1_02735) prkB 4060582..4061451 (+) 870 WP_001274680.1 phosphoribulokinase -
  EC95NR1_RS21930 (EC95NR1_02736) yhfA 4061506..4061910 (-) 405 WP_001148909.1 OsmC family protein -
  EC95NR1_RS21940 (EC95NR1_02737) crp 4062212..4062844 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  EC95NR1_RS21945 (EC95NR1_02738) yhfK 4062895..4064985 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  EC95NR1_RS21950 (EC95NR1_02739) argD 4065052..4066272 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  EC95NR1_RS21955 (EC95NR1_02740) pabA 4066358..4066921 (-) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  EC95NR1_RS21960 (EC95NR1_02741) fic 4066953..4067555 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  EC95NR1_RS21965 (EC95NR1_02742) yhfG 4067545..4067712 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=192769 EC95NR1_RS21940 WP_000242755.1 4062212..4062844(+) (crp) [Escherichia coli strain 95NR1]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=192769 EC95NR1_RS21940 WP_000242755.1 4062212..4062844(+) (crp) [Escherichia coli strain 95NR1]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment