Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilQ   Type   Machinery gene
Locus tag   A6L58_RS00025 Genome accession   NZ_CP016682
Coordinates   2469..4730 (+) Length   753 a.a.
NCBI ID   WP_002258690.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M24705     
Function   pseudopilus extrusion and retraction (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1..9730
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L58_RS00010 (A6L58_00010) pilN 640..1239 (+) 600 WP_002214520.1 PilN domain-containing protein Machinery gene
  A6L58_RS00015 (A6L58_00015) - 1240..1887 (+) 648 WP_002217908.1 type 4a pilus biogenesis protein PilO -
  A6L58_RS00020 (A6L58_00020) pilP 1905..2450 (+) 546 WP_002214522.1 pilus assembly protein PilP Machinery gene
  A6L58_RS00025 (A6L58_00025) pilQ 2469..4730 (+) 2262 WP_002258690.1 type IV pilus secretin PilQ Machinery gene
  A6L58_RS00030 (A6L58_00030) - 5908..6420 (+) 513 WP_002219790.1 shikimate kinase -
  A6L58_RS00035 (A6L58_00035) aroB 6500..7579 (+) 1080 WP_002219791.1 3-dehydroquinate synthase -

Sequence

Protein


Download         Length: 753 a.a.        Molecular weight: 80941.36 Da        Isoelectric Point: 10.0237

>NTDB_id=191700 A6L58_RS00025 WP_002258690.1 2469..4730(+) (pilQ) [Neisseria meningitidis strain M24705]
MNTKLTKIISGLFVATAAFQTASAGNITDIKVSSLPNKQKIVKVSFDKEIVNPTGFVTSSPARIALDFEQTGISMDQQVL
EYADPLLSKISAAQNSSRARLVLNLNKPGQYNTEVRGNKVWIFINESDDTVSAPARPAVKAAPAAPAKQQAAAPSTKSAV
SVSEPFTPAKQQAAAPFTESVVSVSAPFSPAKQQAAASAKQQAAAPAKQTNIDFRKDGKNAGIIELAALGFAGQPDISQQ
HDHIIVTLKNHTLPTTLQRSLDVADFKTPVQKVTLKRLNNDTQLIITTAGNWELVNKSAAPGYFTFQVLPKKQNLESGGV
NNAPKTFTGRKISLDFQDVEIRTILQILAKESGMNIVASDSVNGKMTLSLKDVPWDQALDLVMQARNLDMRQQGNIVNIA
PRDELLAKDKALLQAEKDIADLGALYSQNFQLKYKNVEEFRSILRLDNADTTGNRNTLISGRGSVLIDPATNTLIVTDTR
SVIEKFRKLIDELDVPAQQVMIEARIVEAADGFSRDLGVKFGATGKKKLKNDTSAFGWGVNSGFGGDDKWGAETKINLPI
TAAANSISLVRAISSGALNLELSASESLSKTKTLANPRVLTQNRKEAKIESGYEIPFTVTSIANGGSSTNTELKKAVLGL
TVTPNITPDGQIIMTVKINKDSPAQCASGNQTILCISTKNLNTQAMVENGGTLIVGGIYEEDNGNTLTKVPLLGDIPVIG
NLFKTRGKKTDRRELLIFITPRIMGTAGNSLRY

Nucleotide


Download         Length: 2262 bp        

>NTDB_id=191700 A6L58_RS00025 WP_002258690.1 2469..4730(+) (pilQ) [Neisseria meningitidis strain M24705]
ATGAATACCAAACTGACAAAAATCATTTCCGGTCTCTTTGTCGCAACCGCCGCCTTTCAGACAGCATCGGCAGGAAACAT
TACAGACATCAAAGTTTCCTCCCTGCCCAACAAACAGAAAATCGTCAAAGTCAGCTTTGACAAAGAGATTGTCAACCCGA
CCGGCTTCGTAACCTCCTCACCGGCCCGCATCGCCTTGGACTTTGAACAAACCGGCATTTCCATGGATCAACAGGTACTC
GAATATGCCGATCCTCTGTTGAGCAAAATCAGTGCCGCACAAAACAGCAGCCGTGCGCGTCTGGTTCTGAATCTGAACAA
ACCGGGCCAATACAATACCGAAGTACGCGGGAACAAAGTTTGGATATTCATTAACGAATCGGACGATACCGTGTCCGCCC
CCGCACGCCCCGCCGTAAAAGCCGCGCCTGCCGCACCGGCAAAACAACAGGCTGCCGCACCGTCTACCAAGTCCGCAGTA
TCCGTATCCGAACCCTTTACCCCGGCAAAACAACAGGCTGCCGCACCGTTTACCGAGTCCGTAGTATCCGTATCCGCACC
GTTCAGCCCGGCAAAACAACAGGCGGCGGCATCAGCAAAACAACAGGCGGCAGCACCAGCAAAACAAACCAATATCGATT
TCCGCAAAGACGGCAAAAATGCCGGCATTATCGAATTGGCTGCATTGGGCTTTGCCGGGCAGCCCGACATCAGCCAACAG
CACGACCACATCATCGTTACGCTGAAAAACCATACCCTGCCGACCACGCTCCAACGCAGTTTGGATGTGGCAGACTTTAA
AACACCGGTTCAAAAGGTTACGCTGAAACGCCTCAATAACGACACCCAGCTGATTATCACAACAGCCGGCAACTGGGAAC
TCGTCAACAAATCCGCCGCGCCCGGATACTTTACCTTCCAAGTCCTGCCGAAAAAACAAAACCTCGAGTCAGGCGGCGTG
AACAATGCGCCCAAAACCTTCACAGGCCGGAAAATCTCCCTTGACTTCCAAGATGTCGAAATCCGCACCATCCTGCAGAT
TTTGGCAAAAGAATCCGGAATGAACATTGTTGCCAGCGACTCCGTCAACGGCAAAATGACCCTCTCCCTCAAGGATGTGC
CTTGGGATCAGGCTTTGGATTTGGTTATGCAGGCGCGCAACCTCGATATGCGCCAGCAAGGGAATATCGTCAACATCGCG
CCCCGCGACGAGCTGCTTGCCAAAGACAAAGCCCTCTTACAGGCAGAAAAAGACATTGCCGATTTGGGTGCGCTGTATTC
CCAAAACTTCCAGTTGAAATACAAAAATGTGGAAGAATTCCGCAGCATCCTGCGTTTGGACAATGCCGACACGACCGGAA
ACCGCAACACGCTTATCAGCGGCAGGGGCAGCGTGCTGATCGATCCCGCCACCAACACCCTGATTGTTACCGACACCCGC
AGCGTCATCGAAAAATTCCGCAAACTGATTGACGAATTGGACGTACCCGCGCAACAAGTGATGATTGAGGCGCGTATCGT
CGAAGCGGCAGACGGCTTCTCGCGCGATTTGGGCGTTAAATTCGGCGCGACAGGCAAGAAAAAGCTGAAAAATGATACAA
GCGCATTCGGCTGGGGGGTAAACTCCGGCTTCGGCGGCGACGATAAATGGGGGGCCGAAACCAAAATCAACCTGCCGATT
ACCGCTGCCGCAAACAGCATTTCGCTGGTGCGCGCGATTTCCTCCGGTGCCTTGAATTTGGAATTGTCCGCATCCGAATC
GCTTTCAAAAACCAAAACGCTTGCCAATCCGCGCGTGCTGACCCAAAACCGCAAAGAGGCCAAAATCGAATCCGGTTACG
AAATTCCTTTCACCGTAACCTCAATCGCGAACGGCGGCAGCAGCACGAACACGGAACTCAAAAAAGCCGTCTTGGGGCTG
ACCGTTACGCCGAACATCACGCCCGACGGCCAAATCATTATGACCGTCAAAATCAACAAGGACTCGCCTGCGCAATGTGC
CTCCGGTAATCAGACGATCCTGTGTATTTCGACCAAAAACCTGAATACGCAGGCTATGGTTGAAAACGGCGGCACATTGA
TTGTCGGCGGTATTTATGAAGAAGACAACGGCAATACGCTGACCAAAGTCCCCCTGTTGGGCGACATCCCCGTTATCGGC
AACCTCTTTAAAACACGCGGGAAAAAAACCGACCGCCGCGAACTGCTGATTTTCATTACCCCGAGGATTATGGGTACGGC
CGGCAACAGCCTGCGCTATTGA

Domains

Predicted by InterproScan.

Secretin and TonB N terminus short domain (STN)

(355-400)

Bacterial type II/III secretion system short domain (Secretin_N)

(428-499)

Bacterial type II and III secretion system protein (Secretin)

(585-744)

AMIN domain (AMIN)

(43-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilQ Neisseria meningitidis MC58

97.919

100

1
  pilQ Neisseria meningitidis M1080

98.423

100

0.995
  pilQ Neisseria gonorrhoeae strain FA1090

91.633

100

0.916

Multiple sequence alignment