Detailed information    

insolico Bioinformatically predicted

Overview

Name   dsbA2   Type   Machinery gene
Locus tag   A6L95_RS10295 Genome accession   NZ_CP016677
Coordinates   1982292..1982987 (-) Length   231 a.a.
NCBI ID   WP_002215704.1    Uniprot ID   Q7DDR6
Organism   Neisseria meningitidis strain M25456     
Function   DNA binding and uptake; interact with PilQ (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1970702..1983817 1982292..1982987 within 0


Gene organization within MGE regions


Location: 1970702..1983817
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L95_RS10225 (A6L95_10225) - 1971160..1971417 (+) 258 WP_002241061.1 membrane protein -
  A6L95_RS10230 (A6L95_10230) - 1971399..1971608 (-) 210 Protein_1916 transposase -
  A6L95_RS10235 (A6L95_10235) - 1971773..1972426 (-) 654 WP_002241060.1 IS1595 family transposase -
  A6L95_RS14105 (A6L95_10240) - 1972546..1972752 (-) 207 WP_002220254.1 hypothetical protein -
  A6L95_RS10245 (A6L95_10245) - 1972984..1973190 (-) 207 WP_025461473.1 hypothetical protein -
  A6L95_RS10250 (A6L95_10250) comE 1973302..1973766 (-) 465 WP_181778300.1 ComEA family DNA-binding protein Machinery gene
  A6L95_RS10285 (A6L95_10285) - 1979565..1980371 (-) 807 WP_002221447.1 cytochrome C assembly family protein -
  A6L95_RS10290 (A6L95_10290) ffh 1980591..1981961 (+) 1371 WP_002221448.1 signal recognition particle protein -
  A6L95_RS10295 (A6L95_10295) dsbA2 1982292..1982987 (-) 696 WP_002215704.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  A6L95_RS10300 (A6L95_10300) - 1983158..1983817 (-) 660 WP_002218694.1 NYN domain-containing protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 25419.90 Da        Isoelectric Point: 5.1502

>NTDB_id=191504 A6L95_RS10295 WP_002215704.1 1982292..1982987(-) (dsbA2) [Neisseria meningitidis strain M25456]
MKLKTLALTSLTLLALAACSKQAETSVPADSAQSSSSAPAAPAELNEGVNYTVLSTPIPQQQAGKIEVLEFFGYFCPHCA
HLEPVLSEHIKTFKDDTYMRREHVVWGDEMKPLARLAAAVEMAGESDKANSHIFDAMVNQKINLADTDTLKKWLSEQTAF
DGKKVLAAFEAPESQARAAQMEELTNKFQISGTPTVIVGGKYQVEFKDWQSGMTTIDQLVDKVREEQKKPQ

Nucleotide


Download         Length: 696 bp        

>NTDB_id=191504 A6L95_RS10295 WP_002215704.1 1982292..1982987(-) (dsbA2) [Neisseria meningitidis strain M25456]
ATGAAACTGAAAACCTTAGCTTTGACTTCATTGACCCTGTTGGCATTGGCCGCTTGTAGCAAACAGGCTGAAACCAGTGT
TCCGGCAGACAGCGCCCAAAGCAGCTCATCTGCTCCGGCAGCCCCTGCTGAGTTGAACGAAGGTGTGAACTACACTGTAT
TGTCTACGCCTATTCCGCAACAGCAGGCCGGTAAAATCGAAGTATTGGAATTTTTCGGCTACTTCTGCCCGCATTGCGCC
CATCTTGAGCCGGTCTTGAGCGAGCACATCAAAACGTTTAAAGACGATACCTATATGCGCCGGGAGCATGTCGTGTGGGG
TGATGAAATGAAACCTTTGGCACGTTTGGCGGCCGCAGTGGAAATGGCCGGTGAATCAGATAAAGCCAACAGCCATATTT
TCGATGCGATGGTTAATCAAAAAATCAATCTGGCCGATACCGATACCCTGAAAAAATGGCTGTCCGAGCAAACAGCGTTT
GACGGCAAAAAAGTATTGGCTGCATTTGAGGCTCCTGAAAGCCAAGCGCGTGCGGCTCAAATGGAAGAGTTGACCAATAA
ATTCCAAATCAGCGGCACACCGACTGTGATTGTCGGCGGCAAATACCAAGTTGAATTTAAAGACTGGCAGTCTGGTATGA
CCACGATTGACCAGTTGGTGGATAAAGTACGCGAAGAGCAGAAAAAGCCGCAATAA

Domains

Predicted by InterproScan.

Thioredoxin (Thioredoxin_4)

(65-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q7DDR6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dsbA2 Neisseria meningitidis MC58

100

100

1
  dsbA1 Neisseria meningitidis MC58

71.245

100

0.719

Multiple sequence alignment