Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   A6L95_RS10250 Genome accession   NZ_CP016677
Coordinates   1973302..1973766 (-) Length   154 a.a.
NCBI ID   WP_181778300.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M25456     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1970702..1983817 1973302..1973766 within 0
IS/Tn 1971773..1972426 1973302..1973766 flank 876


Gene organization within MGE regions


Location: 1970702..1983817
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L95_RS10225 (A6L95_10225) - 1971160..1971417 (+) 258 WP_002241061.1 membrane protein -
  A6L95_RS10230 (A6L95_10230) - 1971399..1971608 (-) 210 Protein_1916 transposase -
  A6L95_RS10235 (A6L95_10235) - 1971773..1972426 (-) 654 WP_002241060.1 IS1595 family transposase -
  A6L95_RS14105 (A6L95_10240) - 1972546..1972752 (-) 207 WP_002220254.1 hypothetical protein -
  A6L95_RS10245 (A6L95_10245) - 1972984..1973190 (-) 207 WP_025461473.1 hypothetical protein -
  A6L95_RS10250 (A6L95_10250) comE 1973302..1973766 (-) 465 WP_181778300.1 ComEA family DNA-binding protein Machinery gene
  A6L95_RS10285 (A6L95_10285) - 1979565..1980371 (-) 807 WP_002221447.1 cytochrome C assembly family protein -
  A6L95_RS10290 (A6L95_10290) ffh 1980591..1981961 (+) 1371 WP_002221448.1 signal recognition particle protein -
  A6L95_RS10295 (A6L95_10295) dsbA2 1982292..1982987 (-) 696 WP_002215704.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  A6L95_RS10300 (A6L95_10300) - 1983158..1983817 (-) 660 WP_002218694.1 NYN domain-containing protein -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16501.79 Da        Isoelectric Point: 10.9585

>NTDB_id=191503 A6L95_RS10250 WP_181778300.1 1973302..1973766(-) (comE) [Neisseria meningitidis strain M25456]
MLCPEKMSGMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKAPAKPVLPAAKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=191503 A6L95_RS10250 WP_181778300.1 1973302..1973766(-) (comE) [Neisseria meningitidis strain M25456]
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACGGCATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACCCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCTGTCGGCGCGCCCGCACCAAAAGCCCCAGCCAAACCGGTGCTGCCCGCAGCTAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74

Multiple sequence alignment