Detailed information NTG0191217

Bioinformatically predicted

Overview

• Name: comP
• Type: Machinery gene
• Locus tag: A6L42_RS10270
• Genome accession: NZ_CP016671
• Coordinates: 1955744..1956193 (+)
• Length: 149 a.a.
• NCBI ID: WP_002214937.1
• Uniprot ID: A0AA44U8B7
• Organism: Neisseria meningitidis strain M22783
• Function: DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1957179..1958392	1955744..1956193	flank	986

Gene organization within MGE regions

Location: 1955744..1958392

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6L42_RS10270 (A6L42_10270)	comP	1955744..1956193 (+)	450	WP_002214937.1	type IV pilin protein	Machinery gene
A6L42_RS14885 (A6L42_10275)	-	1956283..1956623 (-)	341	Protein_1898	5'-nucleotidase	-
A6L42_RS10280 (A6L42_10280)	-	1956735..1956947 (-)	213	WP_002224145.1	SWIM zinc finger family protein	-
A6L42_RS10285 (A6L42_10285)	-	1957179..1957652 (+)	474	Protein_1900	transposase	-

Sequence

Protein

• Length: 149 a.a.
• Molecular weight: 16834.81 Da
• Isoelectric Point: 9.7951

>NTDB_id=191217 A6L42_RS10270 WP_002214937.1 1955744..1956193(+) (comP) [Neisseria meningitidis strain M22783]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide

• Length: 450 bp

>NTDB_id=191217 A6L42_RS10270 WP_002214937.1 1955744..1956193(+) (comP) [Neisseria meningitidis strain M22783]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCCTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterproScan.

• Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS) (28-107)

• Prokaryotic N-terminal methylation motif (N_methyl) (1-27)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comP	Neisseria gonorrhoeae MS11	100	100	1
comP	Neisseria meningitidis 8013	99.329	100	0.993
comP	Neisseria subflava NJ9703	49.66	98.658	0.49