Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   CAC37_RS03680 Genome accession   NZ_CP021178
Coordinates   774251..776236 (+) Length   661 a.a.
NCBI ID   WP_000229253.1    Uniprot ID   A0A0H2XGZ8
Organism   Staphylococcus aureus subsp. aureus ST398 strain 2012-3     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 769251..781236
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CAC37_RS03655 (CAC37_03815) - 770096..770215 (+) 120 WP_031774844.1 hypothetical protein -
  CAC37_RS03660 (CAC37_03820) prfB 770370..771480 (+) 1111 WP_010956549.1 peptide chain release factor 2 -
  CAC37_RS03665 (CAC37_03825) - 772086..772925 (+) 840 WP_000749384.1 COG3942 and LysM peptidoglycan-binding domain-containing protein -
  CAC37_RS03670 (CAC37_03830) - 773099..773749 (+) 651 WP_000538141.1 YfbR-like 5'-deoxynucleotidase -
  CAC37_RS03675 (CAC37_03835) - 773746..773982 (+) 237 WP_000638419.1 CsbA family protein -
  CAC37_RS03680 (CAC37_03840) uvrB 774251..776236 (+) 1986 WP_000229253.1 excinuclease ABC subunit UvrB Machinery gene
  CAC37_RS03685 (CAC37_03845) uvrA 776244..779090 (+) 2847 WP_000662684.1 excinuclease ABC subunit UvrA Machinery gene
  CAC37_RS03690 (CAC37_03860) hprK 779700..780632 (+) 933 WP_000958224.1 HPr(Ser) kinase/phosphatase -

Sequence

Protein


Download         Length: 661 a.a.        Molecular weight: 76648.34 Da        Isoelectric Point: 5.0538

>NTDB_id=191040 CAC37_RS03680 WP_000229253.1 774251..776236(+) (uvrB) [Staphylococcus aureus subsp. aureus ST398 strain 2012-3]
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFK
EFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLV
VSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKER
EHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPL
GSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGP
YEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSE
IKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTD
SMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAK
DLDFEKATELRDMLFELKAEG

Nucleotide


Download         Length: 1986 bp        

>NTDB_id=191040 CAC37_RS03680 WP_000229253.1 774251..776236(+) (uvrB) [Staphylococcus aureus subsp. aureus ST398 strain 2012-3]
ATGGTTGAACATTATCCTTTTAAAATACATTCTGATTTTGAGCCTCAAGGTGACCAACCGCAAGCAATTAAGGAAATCGT
GGAAGGTATTAAAGCGGGGAAAAGACATCAAACTTTATTAGGTGCAACTGGCACAGGGAAAACATTTACGATGAGTAATG
TTATTAAAGAAGTTGGAAAACCAACATTAATTATCGCGCATAACAAAACATTAGCAGGACAATTATATAGTGAGTTTAAA
GAATTTTTTCCTGAAAACAGGGTGGAATACTTTGTAAGTTACTATGATTATTATCAACCTGAGGCATACGTACCGTCTAC
TGACACTTTTATTGAAAAAGATGCCTCAATCAATGATGAAATTGATCAACTACGACATTCTGCTACAAGTGCATTATTTG
AACGCGATGATGTAATTATTATTGCTAGTGTAAGTTGTATATATGGTTTAGGTAATCCTGAAGAATATAAAGATTTAGTA
GTAAGTGTTCGAGTTGGTATGGAAATGGATAGAAGCGAATTACTTAGAAAACTTGTAGATGTGCAATATACACGAAATGA
CATCGATTTCCAACGAGGAACGTTTCGAGTGCGTGGTGATGTAGTTGAAATATTCCCAGCCTCTAAAGAAGAACTTTGTA
TAAGGGTTGAGTTTTTCGGTGATGAGATTGACCGAATTCGAGAAGTTAACTACCTAACAGGTGAAGTGTTGAAAGAAAGA
GAACATTTTGCGATATTCCCAGCTTCTCACTTCGTAACACGTGAAGAAAAGTTGAAAGTTGCGATTGAACGTATTGAAAA
AGAATTGGAAGAACGATTGAAAGAATTACGAGATGAGAATAAATTACTAGAAGCGCAAAGGTTAGAACAGCGTACCAACT
ATGATTTAGAAATGATGCGAGAGATGGGATTCTGTTCAGGAATTGAAAACTATTCCGTACATTTAACTTTGCGACCACTG
GGTTCGACACCATATACTTTATTGGATTACTTTGGCGATGATTGGTTAGTAATGATTGATGAATCACATGTGACATTACC
GCAAGTTCGAGGCATGTATAACGGAGACAGAGCGCGTAAACAAGTTTTGGTGGATCATGGATTTAGATTGCCGAGTGCAT
TAGATAACCGTCCACTTAAATTTGAAGAATTTGAAGAAAAGACAAAACAACTTGTGTATGTATCTGCAACGCCTGGACCA
TACGAAATTGAACATACGGATAAGATGGTTGAACAAATTATTCGTCCTACTGGTTTACTGGATCCTAAGATTGAGGTTAG
ACCTACTGAAAATCAAATTGACGATTTATTAAGTGAAATTCAAACAAGGGTTGAGCGTAATGAACGCGTACTTGTTACAA
CGCTCACTAAAAAGATGAGTGAAGATTTAACCACATACATGAAAGAAGCGGGTATTAAAGTTAATTATCTGCATTCAGAA
ATCAAGACATTAGAACGAATCGAAATAATTAGAGACTTACGAATGGGTACATATGATGTTATCGTAGGTATTAATTTATT
AAGAGAGGGTATTGATATACCAGAAGTTTCTCTAGTTGTCATATTAGATGCAGATAAAGAAGGATTTTTACGTTCTAACC
GCTCATTAATTCAAACAATAGGTAGAGCTGCGCGTAACGATAAAGGTGAAGTCATTATGTATGCCGATAAAATGACTGAT
TCGATGAAGTATGCAATTGATGAGACACAACGTCGTCGAGAAATACAGATGAAACATAATGAAAAACATGGTATTACACC
TAAAACAATTAATAAAAAAATACATGATTTAATTAGTGCTACTGTTGAAAATGACGAAAATAATGACAAAGCACAAACTG
TGATACCTAAGAAGATGACGAAAAAAGAACGTCAAAAGACAATCGACAATATAGAAAAAGAAATGAAACAAGCAGCGAAA
GATTTAGATTTCGAGAAAGCTACAGAATTAAGAGATATGTTATTTGAATTAAAAGCAGAAGGGTGA

Domains

Predicted by InterProScan.

Helicase conserved C-terminal domain (Helicase_C)

(434-546)

Ultra-violet resistance protein B (UvrB)

(553-594)

Type III restriction enzyme, res subunit (ResIII)

(14-140)

UvrB/uvrC motif (UVR)

(626-659)

UvrB interaction domain (UvrB_inter)

(161-251)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XGZ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

67.534

98.79

0.667
  uvrB Streptococcus pneumoniae TIGR4

67.534

98.79

0.667
  uvrB Streptococcus pneumoniae D39

67.534

98.79

0.667

Multiple sequence alignment