Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   B9N48_RS06790 Genome accession   NZ_CP021169
Coordinates   1280274..1281623 (-) Length   449 a.a.
NCBI ID   WP_086343741.1    Uniprot ID   -
Organism   Bacillus subtilis strain TLO3     
Function   degrading CSP; selective degradation of ComEA and ComEC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1275274..1286623
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B9N48_RS06775 mhqA 1275417..1276367 (+) 951 WP_041344800.1 ring-cleaving dioxygenase -
  B9N48_RS20565 - 1276468..1276614 (+) 147 WP_003244977.1 hypothetical protein -
  B9N48_RS06780 ykcB 1276622..1278772 (+) 2151 WP_086343740.1 glycosyltransferase family 39 protein -
  B9N48_RS06785 gtcC 1278784..1279755 (+) 972 WP_015715747.1 glycosyltransferase family 2 protein -
  B9N48_RS06790 htrA 1280274..1281623 (-) 1350 WP_086343741.1 serine protease HtrA Regulator
  B9N48_RS06795 proG 1281792..1282610 (+) 819 WP_086343742.1 pyrroline-5-carboxylate reductase ProG -
  B9N48_RS06800 dppA 1282739..1283563 (+) 825 WP_014479576.1 D-aminopeptidase DppA -
  B9N48_RS06805 dppB 1283580..1284506 (+) 927 WP_003245446.1 dipeptide ABC transporter permease DppB -
  B9N48_RS06810 dppC 1284512..1285474 (+) 963 WP_014476568.1 dipeptide ABC transporter permease DppC -
  B9N48_RS06815 dppD 1285479..1286486 (+) 1008 WP_086343743.1 dipeptide ABC transporter ATP-binding subunit DppD -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 47790.71 Da        Isoelectric Point: 4.5510

>NTDB_id=190754 B9N48_RS06790 WP_086343741.1 1280274..1281623(-) (htrA) [Bacillus subtilis strain TLO3]
MDNYRDENRTKGNENEVFLTKENNQSASYSARNVIHDQEKKKRGFGWFRPLLGGVIGGSLALGIYTFTPLGDHDSQDTAK
QSSSQQQTQSVTATSTSXEXXXSSXSSSAFKSEDSSKISDMVEDLSPAIVGITNLQAQSNSSLFGSSSSDSSEDTESGSG
SGVIFKKENGKAYIITNNHVVEGASSLKVSLYDGTEVTAKLVGSDSLTDLAVLQISDDHVTKVANFGDSSDLRTGETVIA
IGDPLGKDLSRTVTQGIVSGVDRTVSMSTSAGETSINVIQTDAAINPGNSGGPLLNTDGKIVGINSMKISEDDVEGIGFA
IPSNDVKPIAEELLSKGQIERPYIGVSMLDLEQVPQNYQEGTLGLFGSQLNKGVYIREVASGSPAEKAGLKAEDIIIGLK
GKEIDTGSELRNILYKDAKIGDTVEVKILRNGKEMTKKIKLDQKEEKTS

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=190754 B9N48_RS06790 WP_086343741.1 1280274..1281623(-) (htrA) [Bacillus subtilis strain TLO3]
ATGGATAACTATCGTGATGAAAACAGAACGAAAGGTAATGAGAATGAGGTCTTTTTAACGAAAGAGAACAATCAGAGCGC
CTCCTACTCGGCCCGCAATGTCATTCATGATCAGGAGAAGAAAAAACGAGGATTCGGATGGTTCAGACCGTTGCTTGGCG
GAGTGATCGGCGGCAGTCTCGCCCTTGGCATTTACACGTTTACACCGCTTGGCGACCATGATTCTCAGGACACTGCAAAA
CAATCATCCAGCCAGCAGCAAACGCAATCTGTTACAGCAACAAGCACCTCCWCWGAAWSYWMAWMAAGCTCAASMAGCTC
ATCTGCATTCAAGAGCGAGGACTCTTCTAAAATCTCAGATATGGTAGAAGACCTTTCACCAGCGATTGTCGGTATTACAA
ATCTTCAGGCACAATCAAACAGCTCTTTGTTCGGCTCTAGTTCTTCTGATTCCAGCGAAGATACAGAAAGCGGTTCAGGG
TCAGGTGTCATTTTCAAAAAAGAGAATGGCAAGGCTTATATCATTACAAATAACCACGTCGTAGAAGGGGCATCATCACT
GAAGGTATCTTTATATGACGGCACTGAGGTTACTGCAAAGCTGGTAGGCAGTGACTCGTTAACTGATTTAGCCGTCCTCC
AAATCAGTGATGACCACGTCACAAAAGTGGCAAACTTCGGTGATTCATCTGATCTCAGAACAGGCGAGACCGTTATTGCG
ATTGGGGATCCGCTTGGAAAAGATCTGTCCCGCACAGTAACACAAGGAATTGTAAGCGGCGTGGACAGAACGGTTTCAAT
GTCTACATCAGCCGGCGAAACGAGCATTAACGTCATTCAGACAGACGCAGCAATTAATCCAGGTAACAGCGGCGGTCCTT
TGTTAAATACAGACGGCAAAATTGTCGGCATTAACAGTATGAAAATCAGTGAGGATGATGTTGAGGGTATCGGATTCGCC
ATTCCAAGCAATGACGTAAAACCGATTGCTGAAGAATTGCTGTCTAAAGGACAAATTGAACGTCCATATATCGGTGTCAG
CATGCTTGATCTAGAGCAAGTGCCGCAAAATTACCAAGAAGGCACACTCGGCCTGTTCGGCAGCCAGCTGAATAAAGGTG
TTTACATCCGTGAGGTCGCTTCAGGCTCTCCTGCTGAAAAGGCCGGATTAAAAGCGGAGGATATTATCATCGGCCTAAAA
GGTAAAGAAATTGATACAGGCAGTGAATTGCGCAATATCTTATATAAAGACGCAAAGATCGGTGATACCGTTGAAGTGAA
AATTCTCCGAAACGGCAAAGAAATGACGAAAAAAATTAAACTGGATCAAAAAGAAGAGAAAACTTCGTAA

Domains

Predicted by InterProScan.

Peptidase family M50 (Peptidase_M50)

(364-448)

PDZ domain (PDZ_2)

(342-441)

Trypsin-like peptidase domain (Trypsin_2)

(160-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus pneumoniae Rx1

41.045

89.532

0.367
  htrA Streptococcus pneumoniae D39

41.045

89.532

0.367
  htrA Streptococcus pneumoniae R6

41.045

89.532

0.367
  htrA Streptococcus pneumoniae TIGR4

41.045

89.532

0.367
  htrA Streptococcus mitis NCTC 12261

39.563

91.759

0.363

Multiple sequence alignment